Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.62 |
| ▸ | ERBB2 | P04626 | 8/20 | 0.58 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.56 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.56 |
| ▸ | RET | P07949 | 1/20 | 0.56 |
| ▸ | MET | P08581 | 1/20 | 0.56 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.56 |
| ▸ | TEC | P42680 | 1/20 | 0.56 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.56 |
| ▸ | EPHA4 | P54764 | 1/20 | 0.56 |
| ▸ | BTK | Q06187 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.56 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27152211 | 1.00 | EGFR (0.62) | EGFRERBB2EPHA2RIPK2RET | |
| SCHEMBL30822092 | 0.95 | EGFR (0.56) | EGFRERBB2EPHA2RIPK2RET | |
| SCHEMBL27136650 | 0.95 | EGFR (0.56) | EGFRERBB2EPHA2RIPK2RET | |
| SCHEMBL27148662 | 0.92 | EPHA2 (0.57) | EGFRERBB2EPHA2 | |
| SCHEMBL30032119 | 0.92 | EPHA2 (0.57) | EGFRERBB2EPHA2 | |
| SCHEMBL30820474 | 0.92 | EPHA2 (0.57) | EGFRERBB2EPHA2 | |
| SCHEMBL24714566 | 0.88 | EPHA2 (0.52) | EGFRERBB2EPHA2EPHB4 | |
| SCHEMBL16075714 | 0.87 | EGFR (0.76) | EGFRERBB2RET | |
| SCHEMBL30820403 | 0.87 | EGFR (0.81) | EGFRERBB2RIPK2RETMET | |
| SCHEMBL27136364 | 0.87 | EGFR (0.81) | EGFRERBB2RIPK2RETMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693505-A | Heteroaryl derivative compounds and uses thereof | 沃若诺伊公司 | 2024-03-12 | — | — | CN | disclosed |