Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 15/20 | 0.49 |
| ▸ | RET | P07949 | 8/20 | 0.49 |
| ▸ | KIF5B | P33176 | 8/20 | 0.49 |
| ▸ | FLT1 | P17948 | 8/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.48 |
| ▸ | FLT4 | P35916 | 3/20 | 0.48 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 7/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | INSR | P06213 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.44 |
| ▸ | TEK | Q02763 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24714457 | 0.88 | KDR (0.51) | KDRRETKIF5BFLT1FGFR1 | |
| SCHEMBL24714666 | 0.86 | KDR (0.46) | KDRRETKIF5BFLT1FGFR1 | |
| SCHEMBL24713878 | 0.85 | EGFR (0.54) | KDRRETKIF5BFLT1FGFR1 | |
| SCHEMBL24713941 | 0.83 | KDR (0.49) | KDRRETKIF5BFLT1FGFR1 | |
| SCHEMBL24713892 | 0.81 | KDR (0.54) | KDRRETKIF5BFLT1FGFR1 | |
| SCHEMBL24714059 | 0.81 | KDR (0.56) | KDRRETKIF5BFLT1FGFR1 | |
| SCHEMBL24714485 | 0.80 | KDR (0.60) | KDRRETKIF5BFLT1FGFR1 | |
| SCHEMBL24714932 | 0.80 | KDR (0.52) | KDRRETKIF5BFLT1FGFR1 | |
| SCHEMBL24713881 | 0.80 | KDR (0.49) | KDRRETKIF5BFLT1FGFR1 | |
| SCHEMBL24714929 | 0.79 | EGFR (0.54) | KDRRETKIF5BFLT1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022225238-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이 주식회사 | 2022-10-27 | — | — | WO | disclosed |