Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 9/20 | 0.46 |
| ▸ | FLT1 | P17948 | 4/20 | 0.46 |
| ▸ | EGFR | P00533 | 9/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.46 |
| ▸ | RET | P07949 | 7/20 | 0.45 |
| ▸ | KIF5B | P33176 | 5/20 | 0.45 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24714671 | 0.86 | KDR (0.49) | KDRFLT1EGFRFGFR1RET | |
| SCHEMBL24714457 | 0.82 | KDR (0.51) | KDRFLT1EGFRFGFR1RET | |
| SCHEMBL24713878 | 0.82 | EGFR (0.54) | KDRFLT1EGFRFGFR1RET | |
| SCHEMBL24714932 | 0.82 | KDR (0.52) | KDRFLT1EGFRFGFR1RET | |
| SCHEMBL24714620 | 0.81 | KDR (0.48) | KDRFLT1EGFRFGFR1RET | |
| SCHEMBL24714929 | 0.80 | EGFR (0.54) | KDRFLT1EGFRRETKIF5B | |
| SCHEMBL24714059 | 0.80 | KDR (0.56) | KDRFLT1EGFRFGFR1RET | |
| SCHEMBL24714485 | 0.79 | KDR (0.60) | KDRFLT1EGFRFGFR1RET | |
| SCHEMBL24715171 | 0.79 | EGFR (0.61) | KDRFLT1EGFRFGFR1RET | |
| SCHEMBL24713892 | 0.78 | KDR (0.54) | KDRFLT1EGFRFGFR1RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022225238-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이 주식회사 | 2022-10-27 | — | — | WO | disclosed |