Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13535501 | 0.82 | YTHDC1 (0.37) | YTHDC1XDHPDE2A | |
| SCHEMBL23642703 | 0.77 | — | — | |
| SCHEMBL24174504 | 0.73 | PAK4 (0.54) | YTHDC1 | |
| SCHEMBL8188860 | 0.73 | HTT (0.42) | YTHDC1XDH | |
| SCHEMBL25166582 | 0.73 | YTHDC1 (0.46) | YTHDC1XDHPDE2A | |
| SCHEMBL30329676 | 0.73 | YTHDC1 (0.46) | YTHDC1XDHPDE2A | |
| SCHEMBL20302639 | 0.69 | YTHDC1 (0.43) | YTHDC1XDHPDE2A | |
| SCHEMBL22843514 | 0.68 | YTHDC1 (0.38) | YTHDC1XDHPDE2A | |
| SCHEMBL12179644 | 0.67 | — | — | |
| SCHEMBL19933214 | 0.66 | YTHDC1 (0.37) | YTHDC1XDHPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251188-A2 | IMIDAZOLE-CONTAINING INHIBITORS OF ALK2 KINASE | BIOCRYST PHARMACEUTICALS, INC. (US) | 2022-12-01 | — | — | WO | disclosed |