Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30979951 | 0.88 | EGFR (0.52) | EGFRERBB2FGFR1FLT1KDR | |
| SCHEMBL27152038 | 0.88 | EGFR (0.52) | EGFRERBB2FGFR1FLT1KDR | |
| SCHEMBL27140098 | 0.88 | EGFR (0.52) | EGFRERBB2FGFR1FLT1KDR | |
| SCHEMBL24714697 | 0.88 | EGFR (0.52) | EGFRERBB2FGFR1FLT1KDR | |
| SCHEMBL27138422 | 0.88 | EGFR (0.52) | EGFRERBB2FGFR1FLT1KDR | |
| SCHEMBL24715217 | 0.84 | KDR (0.47) | EGFRFGFR1FLT1KDR | |
| SCHEMBL27136436 | 0.81 | EGFR (0.61) | EGFRERBB2 | |
| SCHEMBL27136435 | 0.81 | EGFR (0.61) | EGFRERBB2 | |
| SCHEMBL24714966 | 0.78 | KDR (0.49) | EGFRERBB2FGFR1FLT1KDR | |
| SCHEMBL24713914 | 0.75 | EGFR (0.43) | EGFRERBB2FGFR1FLT1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022225238-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이 주식회사 | 2022-10-27 | — | — | WO | disclosed |