Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 15/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | KIF5B | P33176 | 1/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24714084 | 0.89 | KDR (0.44) | KDRFGFR1FLT1RAF1BRAF | |
| SCHEMBL27139767 | 0.87 | EGFR (0.52) | KDRFGFR1FLT1EGFRERBB2 | |
| SCHEMBL24713914 | 0.85 | EGFR (0.43) | KDRFGFR1FLT1RAF1BRAF | |
| SCHEMBL24715217 | 0.83 | KDR (0.47) | KDRFGFR1FLT1RAF1BRAF | |
| SCHEMBL24714001 | 0.80 | BRAF (0.63) | KDRFGFR1FLT1RAF1BRAF | |
| SCHEMBL24715221 | 0.79 | HDAC3 (0.44) | KDRFGFR1FLT1RAF1BRAF | |
| SCHEMBL24714967 | 0.79 | EGFR (0.50) | KDRFGFR1FLT1EGFRERBB2 | |
| SCHEMBL24713948 | 0.78 | ERBB2 (0.47) | RAF1BRAFEGFRERBB2 | |
| SCHEMBL24714969 | 0.78 | EGFR (0.63) | KDRFGFR1FLT1EGFR | |
| SCHEMBL24714732 | 0.78 | EGFR (0.43) | KDRFGFR1FLT1EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022225238-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이 주식회사 | 2022-10-27 | — | — | WO | disclosed |