SCHEMBL247148

SCHEMBL247148

N#CC=Cc1ccco1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL597212 1.00
SCHEMBL14404891 1.00
SCHEMBL1923276 0.80
SCHEMBL1485961 0.80
SCHEMBL9454441 0.78
SCHEMBL9454436 0.78
SCHEMBL641747 0.78 ALDH1A1 (0.62)
SCHEMBL2789580 0.78 ALDH1A1 (0.62)
SCHEMBL9298131 0.74 F2 (0.67)
SCHEMBL9298138 0.74 F2 (0.67)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3835302-B1 DIISOCYANATE COMPOUND HAVING ANHYDROSUGAR ALCOHOL CORE AND PREPARATION METHOD THEREFOR SAMYANG CORP (KR) 2024-10-02 EP claimed
US-12060364-B2 Diisocyanate compound having anhydrosugar alcohol core and preparation method therefor SAMYANG CORPORATION (KR) 2024-08-13 US claimed
US-20210309670-A1 DIISOCYANATE COMPOUND HAVING ANHYDROSUGAR ALCOHOL CORE AND PREPARATION METHOD THEREFOR SAMYANG CORPORATION (KR) 2021-10-07 US claimed
EP-3835302-A1 DIISOCYANATE COMPOUND HAVING ANHYDROSUGAR ALCOHOL CORE AND PREPARATION METHOD THEREFOR Samyang Corporation (KR) 2021-06-16 EP claimed
CN-109576325-A Conversion of biomass 希乐克公司 2019-04-05 CN claimed
CN-106432151-A Synthesis method of intermediate 2-furan acrylonitrile of fuvinazole drug 厦门莱恩斯特信息科技有限公司 2017-02-22 CN claimed
CN-105503793-A Synthetic method of 2-furanacrylonitrile as fuvinazole drug intermediate CHENGDU ZHONGHENG HUATIE TECH CO LTD 2016-04-20 CN claimed
EP-2870254-A2 CONVERSION OF BIOMASS Xyleco, Inc. (US) 2015-05-13 EP claimed
CN-104508138-A Conversion of biomass XYLECO INC 2015-04-08 CN claimed
WO-2014008364-A2 CONVERSION OF BIOMASS XYLECO, INC. (US) 2014-01-09 WO claimed
EP-1132127-B1 Isolated ultrafine particles TECLE BERHAN (US) 2008-12-24 EP claimed
US-6872754-B1 Method for processing elastomers WORTHAM LEON (US) 2005-03-29 US claimed
US-6372077-B1 COATING A FIBER WITH A POWDER ENCAPSULANT MATERIAL IN A HIGHLY DISPERSED COLLOIDAL SUSPENSION SUCH THAT THE ENCAPSULATED PARTICLES REMAIN INDEPENDENT AND DISCRETE UPON SEPARATION TECLE BERHAN (US) 2002-04-16 US claimed
EP-0917501-B1 METHOD FOR ISOLATING ULTRAFINE AND FINE PARTICLES AND RESULTING PARTICLES TECLE BERHAN (US) 2001-09-19 EP claimed
EP-1132127-A2 Method for isolating ultrafine and fine particles and resulting particles Tecle, Berhan (US) 2001-09-12 EP claimed
US-6190731-B1 FORMING A HIGHLY DISPERSED COLLOIDAL SUSPENSION OF PARTICLES, ADDING TO THE SUSPENSION AN ENCAPSULANT MATERIAL TO ENCAPSULATE INDIVIDUAL PARTICLES, AND ISOLATING FROM SAID SUSPENSION INDEPENDENT ENCAPSULATED PARTICLES Tecle, Berhan 2001-02-20 US claimed
US-5922403-A ADDING ENCAPSULANT TO HIGHLY DISPERSED COLLOIDAL SUSPENSION OF SOLID PARTICLES TO ENCAPSULATE INDIVIDUAL PARTICLES; AGGLOMERATING; ISOLATING ENCAPSULATED PARTICLES BY SEPARATION FROM SOLVENT LAYER TECLE, BERHAN 1999-07-13 US claimed
EP-0917501-A1 METHOD FOR ISOLATING ULTRAFINE AND FINE PARTICLES AND RESULTING PARTICLES Tecle, Berhan (US) 1999-05-26 EP claimed
WO-1997033713-A1 METHOD FOR ISOLATING ULTRAFINE AND FINE PARTICLES AND RESULTING PARTICLES TECLE BERHAN (US) 1997-09-18 WO claimed
CN-122011272-A Soap-free emulsion polymerization method, polymer emulsion and application thereof 重庆硕盈峰新材料科技有限公司 2026-05-12 CN disclosed
CN-118994477-A Palladium complex-containing microgel and preparation method and application thereof 泉州师范学院 2024-11-22 CN disclosed
EP-3835302-B1 DIISOCYANATE COMPOUND HAVING ANHYDROSUGAR ALCOHOL CORE AND PREPARATION METHOD THEREFOR SAMYANG CORP (KR) 2024-10-02 EP disclosed
US-12060364-B2 Diisocyanate compound having anhydrosugar alcohol core and preparation method therefor SAMYANG CORPORATION (KR) 2024-08-13 US disclosed
CN-114057649-B Polymerizable ligand compound, polymer ligand and metal complex thereof 大赛璐(中国)投资有限公司 2023-05-23 CN disclosed
CN-114057649-A Polymerizable ligand compound, polymer ligand and metal complex thereof 大赛璐(中国)投资有限公司 2022-02-18 CN disclosed
US-20210309670-A1 DIISOCYANATE COMPOUND HAVING ANHYDROSUGAR ALCOHOL CORE AND PREPARATION METHOD THEREFOR SAMYANG CORPORATION (KR) 2021-10-07 US disclosed
EP-3835302-A1 DIISOCYANATE COMPOUND HAVING ANHYDROSUGAR ALCOHOL CORE AND PREPARATION METHOD THEREFOR Samyang Corporation (KR) 2021-06-16 EP disclosed
US-10813930-B2 Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3 INCYTE CORPORATION (US) 2020-10-27 US disclosed
WO-2020032611-A1 DIISOCYANATE COMPOUND HAVING ANHYDROSUGAR ALCOHOL CORE AND PREPARATION METHOD THEREFOR 주식회사 삼양사 2020-02-13 WO disclosed
US-20190240220-A1 SUBSTITUTED IMIDAZOPYRIDAZINES AND BENZIMIDAZOLES AS INHIBITORS OF FGFR3 INCYTE CORPORATION 2019-08-08 US disclosed
CN-109576325-A Conversion of biomass 希乐克公司 2019-04-05 CN disclosed
CN-104508138-B Conversion of biomass 希乐克公司 2018-12-11 CN disclosed
EP-3312165-A1 CONVERSION OF BIOMASS Xyleco, Inc. (US) 2018-04-25 EP disclosed
EP-2870254-B1 CONVERSION OF BIOMASS XYLECO INC (US) 2017-09-06 EP disclosed
US-20170165263-A1 SUBSTITUTED IMIDAZOPYRIDAZINES AND BENZIMIDAZOLES AS INHIBITORS OF FGFR3 INCYTE CORPORATION 2017-06-15 US disclosed
CN-106432151-A Synthesis method of intermediate 2-furan acrylonitrile of fuvinazole drug 厦门莱恩斯特信息科技有限公司 2017-02-22 CN disclosed
US-9533954-B2 Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3 INCYTE CORPORATION (US) 2017-01-03 US disclosed
EP-2588521-B1 CROSS-LINKED POLYOLEFIN COMPOSITION BASELL POLIOLEFINE SRL (IT) 2016-10-19 EP disclosed
CN-105503793-A Synthetic method of 2-furanacrylonitrile as fuvinazole drug intermediate CHENGDU ZHONGHENG HUATIE TECH CO LTD 2016-04-20 CN disclosed
CN-105503793-A Synthetic method of 2-furanacrylonitrile as fuvinazole drug intermediate CHENGDU ZHONGHENG HUATIE TECH CO LTD 2016-04-20 CN disclosed
CN-105503793-A Synthetic method of 2-furanacrylonitrile as fuvinazole drug intermediate CHENGDU ZHONGHENG HUATIE TECH CO LTD 2016-04-20 CN disclosed
EP-2588524-B1 CROSS-LINKED POLYOLEFIN COMPOSITION BASELL POLIOLEFINE SRL (IT) 2016-01-06 EP disclosed
EP-1489109-B1 Living and quasiliving cationic telechelic polymers quenched by N-substituted pyrrole and methods for their preparation CHEVRON ORONITE CO (US) 2015-08-19 EP disclosed
EP-2870254-A2 CONVERSION OF BIOMASS Xyleco, Inc. (US) 2015-05-13 EP disclosed
EP-1928456-B1 SUBSTITUTED PYRAZOLE COMPOUNDS MIIKANA THERAPEUTICS INC (US) 2015-04-22 EP disclosed
CN-104508138-A Conversion of biomass XYLECO INC 2015-04-08 CN disclosed
US-20140243308-A1 SUBSTITUTED IMIDAZOPYRIDAZINES AND BENZIMIDAZOLES AS INHIBITORS OF FGFR3 INCYTE CORPORATION (US) 2014-08-28 US disclosed
US-8779063-B2 Cross-linked polyolefin composition BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2014-07-15 US disclosed
US-8754114-B2 Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3 INCYTE CORPORATION (US) 2014-06-17 US disclosed
US-8669327-B2 Cross-linked polyolefin composition BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2014-03-11 US disclosed
WO-2014008364-A2 CONVERSION OF BIOMASS XYLECO, INC. (US) 2014-01-09 WO disclosed
EP-2588524-A1 CROSS-LINKED POLYOLEFIN COMPOSITION Basell Poliolefine Italia S.r.l. (IT) 2013-05-08 EP disclosed
EP-2588521-A1 CROSS-LINKED POLYOLEFIN COMPOSITION Basell Poliolefine Italia S.r.l. (IT) 2013-05-08 EP disclosed
US-20130102735-A1 Cross-Linked Polyolefin Composition Basell Poliolefine Italia, s.r.l. (IT) 2013-04-25 US disclosed
US-20130096261-A1 Cross-Linked Polyolefin Composition Basell Poliolefine Italia, s.r.l. (IT) 2013-04-18 US disclosed
US-20120165305-A1 SUBSTITUTED IMIDAZOPYRIDAZINES AND BENZIMIDAZOLES AS INHIBITORS OF FGFR3 INCYTE CORPORATION 2012-06-28 US disclosed
WO-2012088266-A2 SUBSTITUTED IMIDAZOPYRIDAZINES AND BENZIMIDAZOLES AS INHIBITORS OF FGFR3 INCYTE CORPORATION (US) 2012-06-28 WO disclosed
US-8114870-B2 Method of treating disease states using substituted pyrazole compounds MIIKANA THERAPEUTICS, INC. (US) 2012-02-14 US disclosed
WO-2012000884-A1 CROSS-LINKED POLYOLEFIN COMPOSITION BASELL POLIOLEFINE ITALIA SRL (IT) 2012-01-05 WO disclosed
WO-2012000885-A1 CROSS-LINKED POLYOLEFIN COMPOSITION BASELL POLIOLEFINE ITALIA SRL (IT) 2012-01-05 WO disclosed
US-20090264422-A1 METHOD OF TREATING DISEASE STATES USING SUBSTITUTED PYRAZOLE COMPOUNDS MIIKANA THERAPEUTICS, INC. 2009-10-22 US disclosed
US-7576161-B2 Process for preparing terminally functionalized living and quasiliving cationic telechelic polymers CHEVRON ORONITE COMPANY LLC (US) 2009-08-18 US disclosed
US-7563787-B2 Substituted pyrazole compounds MIIKANA THERAPEUTICS, INC. (US) 2009-07-21 US disclosed
EP-1132127-B1 Isolated ultrafine particles TECLE BERHAN (US) 2008-12-24 EP disclosed
CN-101316587-A Substituted pyrazole compounds MIIKANA THERAPEUTICS INC (US) 2008-12-03 CN disclosed
EP-1928456-A2 SUBSTITUTED PYRAZOLE COMPOUNDS Miikana Therapeutics, Inc. (US) 2008-06-11 EP disclosed
US-20070142368-A1 Substituted pyrazole compounds MIIKANA THERAPEUTICS, INC. 2007-06-21 US disclosed
WO-2007041358-A2 SUBSTITUTED PYRAZOLE COMPOUNDS MIIKANA THERAPEUTICS, INC. (US) 2007-04-12 WO disclosed
US-20050282972-A1 Process for preparing terminally functionalized living and quasiliving cationic telechelic polymers STOKES CASEY D 2005-12-22 US disclosed
US-6969744-B2 Living and quasiliving cationic telechelic polymers quenched by N-substituted pyrrole and methods for their preparation UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2005-11-29 US disclosed
US-6872754-B1 Method for processing elastomers WORTHAM LEON (US) 2005-03-29 US disclosed
EP-1489109-A2 Living and quasiliving cationic telechelic polymers quenched by N-substituted pyrrole and methods for their preparation Chevron Oronite Company LLC (US) 2004-12-22 EP disclosed
US-20030216526-A1 Thermoplastic olefin elastomers and process for their preparation CECCHIN GIULIANO (IT) 2003-11-20 US disclosed
US-6610785-B1 Crystalline propylene-diene polymer amd an amorphous, unsaturated elastomeric olefin polymer, crosslinked with a free radical generator MONTELL NORTH AMERICA INC. 2003-08-26 US disclosed
EP-0821674-B1 CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS SEARLE & CO (US) 2003-08-06 EP disclosed
EP-0940436-B1 Thermoplastic elastomer composition containing an antibloom agent BASELL POLIOLEFINE SPA (IT) 2003-05-21 EP disclosed
US-6444694-B1 ANTIPROLIFERATIVE AGENTS WYETH 2002-09-03 US disclosed
US-6372077-B1 COATING A FIBER WITH A POWDER ENCAPSULANT MATERIAL IN A HIGHLY DISPERSED COLLOIDAL SUSPENSION SUCH THAT THE ENCAPSULATED PARTICLES REMAIN INDEPENDENT AND DISCRETE UPON SEPARATION TECLE BERHAN (US) 2002-04-16 US disclosed
EP-0917501-B1 METHOD FOR ISOLATING ULTRAFINE AND FINE PARTICLES AND RESULTING PARTICLES TECLE BERHAN (US) 2001-09-19 EP disclosed
EP-1132127-A2 Method for isolating ultrafine and fine particles and resulting particles Tecle, Berhan (US) 2001-09-12 EP disclosed
EP-0830345-B1 STYRYL BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION AMERICAN HOME PROD (US) 2001-09-05 EP disclosed
US-6190731-B1 FORMING A HIGHLY DISPERSED COLLOIDAL SUSPENSION OF PARTICLES, ADDING TO THE SUSPENSION AN ENCAPSULANT MATERIAL TO ENCAPSULATE INDIVIDUAL PARTICLES, AND ISOLATING FROM SAID SUSPENSION INDEPENDENT ENCAPSULATED PARTICLES Tecle, Berhan 2001-02-20 US disclosed
US-6150466-A ORGANIC PEROXIDE CROSSLINKING AGENT MONTELL NORTH AMERICA INC. (US) 2000-11-21 US disclosed
EP-0603724-B1 Thermoplastic olefin elastomers and process for their preparation MONTELL NORTH AMERICA INC (US) 2000-08-16 EP disclosed
US-6011028-A Cyclic amidino agents useful as nitric oxide synthase inhibitors G.D. SEARLE & CO. (US) 2000-01-04 US disclosed
EP-0940436-A1 Thermoplastic elastomer composition containing an antibloom agent Montell North America Inc. (US) 1999-09-08 EP disclosed
US-5922403-A ADDING ENCAPSULANT TO HIGHLY DISPERSED COLLOIDAL SUSPENSION OF SOLID PARTICLES TO ENCAPSULATE INDIVIDUAL PARTICLES; AGGLOMERATING; ISOLATING ENCAPSULATED PARTICLES BY SEPARATION FROM SOLVENT LAYER TECLE, BERHAN 1999-07-13 US disclosed
EP-0917501-A1 METHOD FOR ISOLATING ULTRAFINE AND FINE PARTICLES AND RESULTING PARTICLES Tecle, Berhan (US) 1999-05-26 EP disclosed
CN-1040549-C Liquid hard surface detergent compositions containing zwitterionic and cationic detergent, surfactants and monoethanolamine and/or beta-aminoalkanol PROCTER & GAMBLE (US) 1998-11-04 CN disclosed
EP-0633289-B1 Partially cross-linked polyolefin composition MONTELL NORTH AMERICA INC (US) 1998-10-28 EP disclosed
CN-1192206-A Styrylbenzimidazole derivatives as inhibitors of smooth muscle cell proliferation AMERICAN HOME PROD (US) 1998-09-02 CN disclosed
EP-0830345-A1 STYRYL BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION AMERICAN HOME PRODUCTS CORPORATION (US) 1998-03-25 EP disclosed
EP-0821674-A1 CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS G.D. SEARLE &amp; CO. (US) 1998-02-04 EP disclosed
WO-1997033713-A1 METHOD FOR ISOLATING ULTRAFINE AND FINE PARTICLES AND RESULTING PARTICLES TECLE BERHAN (US) 1997-09-18 WO disclosed
US-5665763-A ANTIPICORNAVIRAL AGENTS SANOFI, S.A. (FR) 1997-09-09 US disclosed
EP-0513699-B1 Zinc-salts of certain mercapto compounds as antioxidants for high temperature aging of thermoplastic elastomers MONTELL NORTH AMERICA INC (US) 1997-08-13 EP disclosed
WO-1996039391-A1 STYRYL BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION AMERICAN HOME PRODUCTS CORPORATION (US) 1996-12-12 WO disclosed
US-5567717-A COMBATTING PICORNAVIRUSES STERLING WINTHROP, INC. (US) 1996-10-22 US disclosed
US-5514679-A TREATMENT OF PICORNAVIRUS INFECTIONS STERLING WINTHROP INC. (US) 1996-05-07 US disclosed
WO-1995031439-A1 THERAPEUTIC PHENOXYALKYLPYRIDAZINES AND INTERMEDIATES THEREFOR SANOFI WINTHROP, INC. (US) 1995-11-23 WO disclosed
EP-0472956-B1 Dynamically partially crosslinked thermoplastic elastomer containing polybutene-1 MONTELL NORTH AMERICA INC (US) 1995-10-18 EP disclosed
EP-0450342-B1 Crosslinked polypropylene compositions suitable for the manufacture of foamed articles SPHERILENE SRL (IT) 1995-10-11 EP disclosed
EP-0500653-A4 INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE BIOCRYST INC (US) 1995-08-23 EP disclosed
EP-0361205-B1 Plastoelastomeric polyolefin compositions and process for preparing them HIMONT ITALIA (IT) 1995-05-10 EP disclosed
EP-0633289-A1 Partially cross-linked polyolefin composition MONTELL NORTH AMERICA INC. (US) 1995-01-11 EP disclosed
EP-0603724-A2 Thermoplastic olefin elastomers and process for their preparation MONTELL NORTH AMERICA INC. (US) 1994-06-29 EP disclosed
CN-1078745-A The liquid hard surface detergent compositions that contains tensio-active agent and alkanolamine PROCTER & GAMBLE (US) 1993-11-24 CN disclosed
US-5196462-A Olefin polymers HIMONT INCORPORATED (US) 1993-03-23 US disclosed
EP-0513699-A2 Zinc-salts of certain mercapto compounds as antioxidants for high temperature aging of thermoplastic elastomers MONTELL NORTH AMERICA INC. (US) 1992-11-19 EP disclosed
EP-0500653-A1 INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE BIOCRYST PHARMACEUTICALS INC. (US) 1992-09-02 EP disclosed
US-5143978-A DYNAMICALLY PARTIALLY CROSSLINKED THERMOPLASTIC ELASTOMER CONTAINING POLYBUTENE-1 HIMONT INCORPORATED (US) 1992-09-01 US disclosed
EP-0472956-A2 Dynamically partially crosslinked thermoplastic elastomer containing polybutene-1 MONTELL NORTH AMERICA INC. (US) 1992-03-04 EP disclosed
US-5082869-A Homogeneous, flexible AUSIMONT S.P.A. (IT) 1992-01-21 US disclosed
US-5066700-A Organic Peroxide Vulcanizing Agent, Furan Derivative As A Crosslinking Coadjuvant AUSIMONT S.P.A. (IT) 1991-11-19 US disclosed
EP-0450342-A2 Crosslinked polypropylene compositions suitable for the manufacture of foamed articles SPHERILENE S.r.l. (IT) 1991-10-09 EP disclosed
WO-1991006548-A1 INHIBITORS OF PURINE NUCLEOSIDE PHOSPHORYLASE BIOCRYST, INC. (US) 1991-05-16 WO disclosed
US-5008270-A 2-amino-7-(heterocyclomethyl)-3H,5H-pyrrolo[3,2-d]pyrimidin-4-ones and pharmaceutical uses and compositions containing the same BIOCRYST, INC. (US) 1991-04-16 US disclosed
US-4963612-A Plastoelastomeric polyolefinic compositions and process for preparing them according to dynamic vulcanizable methods AUSIMONT S.R.L. (IT) 1990-10-16 US disclosed
EP-0361205-A2 Plastoelastomeric polyolefin compositions and process for preparing them HIMONT ITALIA S.r.l. (IT) 1990-04-04 EP disclosed
WO-1989002428-A1 ENANTIOSELECTIVE PROCESS ICI AUSTRALIA OPERATIONS PROPRIETARY LIMITED (AU) 1989-03-23 WO disclosed
US-4476332-A HYDROLYTIC REDUCTION OF FURANS ETHYL CORPORATION (US) 1984-10-09 US disclosed
US-4475004-A REDUCTION, HYDROLYSIS, CATALYST ETHYL CORPORATION (US) 1984-10-02 US disclosed
US-4263212-A Process for preparation of substituted olefins RIKAGAKU KENKYUSHO (JP) 1981-04-21 US disclosed
US-4263212-A Process for preparation of substituted olefins RIKAGAKU KENKYUSHO (JP) 1981-04-21 US disclosed