Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.61 |
| ▸ | RET | P07949 | 5/20 | 0.56 |
| ▸ | KDR | P35968 | 4/20 | 0.56 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | FLT1 | P17948 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.50 |
| ▸ | KIF5B | P33176 | 1/20 | 0.50 |
| ▸ | CLK1 | P49759 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.50 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24713989 | 0.93 | EGFR (0.55) | EGFRRETKDRLCKFLT1 | |
| SCHEMBL24714946 | 0.86 | EGFR (0.49) | EGFRRETKDRFLT1FGFR1 | |
| SCHEMBL24713892 | 0.86 | KDR (0.54) | EGFRRETKDRFLT1FGFR1 | |
| SCHEMBL24714641 | 0.86 | EGFR (0.56) | EGFRRETKDRLCKFLT1 | |
| SCHEMBL24714041 | 0.86 | EGFR (0.47) | EGFRRETKDRFLT1FGFR1 | |
| SCHEMBL24714943 | 0.84 | EGFR (0.56) | EGFRRETKDRLCKFLT1 | |
| SCHEMBL24714932 | 0.82 | KDR (0.52) | EGFRRETKDRLCKFLT1 | |
| SCHEMBL24714561 | 0.82 | EGFR (0.54) | EGFRRETKDRFLT1FGFR1 | |
| SCHEMBL24714929 | 0.82 | EGFR (0.54) | EGFRRETKDRLCKFLT1 | |
| SCHEMBL24713875 | 0.79 | EGFR (0.55) | EGFRRETKDRLCKFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022225238-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이 주식회사 | 2022-10-27 | — | — | WO | disclosed |