Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 9/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.44 |
| ▸ | KDR | P35968 | 10/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 9/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24714966 | 0.79 | KDR (0.49) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL24714084 | 0.78 | KDR (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL24715217 | 0.77 | KDR (0.47) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL24714969 | 0.77 | EGFR (0.63) | KDRFGFR1FLT1EGFR | |
| SCHEMBL24714735 | 0.76 | EGFR (0.45) | EGFRMET | |
| SCHEMBL24714310 | 0.76 | EGFR (0.69) | EGFR | |
| SCHEMBL30031190 | 0.76 | EGFR (0.69) | EGFR | |
| SCHEMBL24713884 | 0.74 | KDR (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL24714001 | 0.73 | BRAF (0.63) | KDRFGFR1FLT1EGFRRAF1 | |
| SCHEMBL30032313 | 0.73 | EGFR (0.67) | EGFRMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022225238-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이 주식회사 | 2022-10-27 | — | — | WO | disclosed |