Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30626621 | 0.78 | ALDH1A1 (0.74) | ALDH1A1HSD17B10CASP1CASP7CYP1A2 | |
| SCHEMBL27190053 | 0.78 | ALDH1A1 (0.74) | ALDH1A1HSD17B10CASP1CASP7CYP1A2 | |
| SCHEMBL1758548 | 0.73 | KMT2A (0.57) | ALDH1A1HSD17B10CYP1A2CYP2C19KMT2A | |
| SCHEMBL22621718 | 0.70 | MEN1 (0.53) | ALDH1A1CYP1A2CYP2C19KMT2AMEN1 | |
| SCHEMBL8329121 | 0.67 | KMT2A (0.61) | ALDH1A1HSD17B10CYP1A2GAACYP2C19 | |
| SCHEMBL23565733 | 0.67 | KMT2A (0.61) | ALDH1A1CYP1A2CYP2C19KMT2AMEN1 | |
| SCHEMBL9227908 | 0.65 | KMT2A (0.59) | ALDH1A1HSD17B10CYP1A2GAACYP2C19 | |
| SCHEMBL20083930 | 0.64 | KMT2A (0.57) | ALDH1A1HSD17B10CYP1A2GAACYP2C19 | |
| SCHEMBL5756345 | 0.64 | KMT2A (0.57) | ALDH1A1HSD17B10CYP1A2GAACYP2C19 | |
| SCHEMBL31527841 | 0.64 | KMT2A (0.57) | ALDH1A1HSD17B10CYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253152-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2022-12-08 | — | — | WO | disclosed |