Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792563 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTHTTMITFCTSB | |
| SCHEMBL30626608 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTHTTMITFCTSB | |
| SCHEMBL30792565 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTHTTMITFCTSB | |
| SCHEMBL27190075 | 0.88 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTHTTMITFCTSB | |
| SCHEMBL24716140 | 0.82 | MAPT (0.47) | SMN1; SMN2MAPTHTTMITFCTSB | |
| SCHEMBL28493144 | 0.79 | AR (0.55) | SMN1; SMN2MAPTCTSB | |
| SCHEMBL24715761 | 0.76 | MAPT (0.70) | SMN1; SMN2MAPTHTTMITFCTSB | |
| SCHEMBL696233 | 0.76 | MAPT (0.51) | SMN1; SMN2MAPTHTTTDP1L3MBTL1 | |
| SCHEMBL11477630 | 0.75 | MAPT (0.42) | SMN1; SMN2MAPTHTTPOLBRECQL | |
| SCHEMBL11477620 | 0.74 | MAPT (0.42) | SMN1; SMN2MAPTHTTPOLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253152-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2022-12-08 | — | — | WO | disclosed |