Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 10/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CTSB | P07858 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24716147 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTHTTMITFKDM4E | |
| SCHEMBL30792565 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTHTTMITFKDM4E | |
| SCHEMBL30792563 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTHTTMITFKDM4E | |
| SCHEMBL30626608 | 0.88 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTHTTMITFKDM4E | |
| SCHEMBL24716140 | 0.82 | MAPT (0.47) | SMN1; SMN2MAPTHTTMITFKDM4E | |
| SCHEMBL24715761 | 0.78 | MAPT (0.70) | SMN1; SMN2MAPTHTTMITFKDM4E | |
| SCHEMBL11055247 | 0.74 | SMN1; SMN2 (1.00) | SMN1; SMN2MAPTL3MBTL1POLBALDH1A1 | |
| SCHEMBL9285207 | 0.74 | MEN1 (0.62) | SMN1; SMN2MAPTHTTPOLBRECQL | |
| SCHEMBL24716141 | 0.73 | MAPT (0.55) | SMN1; SMN2MAPTHTTMITFKDM4E | |
| SCHEMBL7978483 | 0.73 | SMN1; SMN2 (0.68) | SMN1; SMN2MAPTKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4349815-A1 | 7-NITRO-8-HYDROXYQUINOLINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Jiangsu Yahong Meditech Co., Ltd. (CN) | 2024-04-10 | — | — | EP | disclosed |