Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 13/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6853361 | 0.85 | CA12 (0.44) | AAK1 | |
| SCHEMBL27407319 | 0.83 | EGLN2 (0.41) | AAK1 | |
| SCHEMBL30175900 | 0.81 | AAK1 (0.49) | AAK1NPC1RECQLRAB9ASMN1; SMN2 | |
| SCHEMBL1519234 | 0.81 | AAK1 (0.49) | AAK1NPC1RECQLRAB9ASMN1; SMN2 | |
| SCHEMBL29430574 | 0.80 | AAK1 (0.65) | AAK1NPC1RECQLRAB9ASMN1; SMN2 | |
| SCHEMBL3565747 | 0.80 | AAK1 (0.65) | AAK1NPC1RECQLRAB9ASMN1; SMN2 | |
| SCHEMBL4975833 | 0.79 | AAK1 (0.52) | AAK1NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13514632 | 0.79 | AAK1 (0.47) | AAK1NPC1RECQLRAB9ASMN1; SMN2 | |
| SCHEMBL31167627 | 0.79 | AAK1 (0.52) | AAK1NPSR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20868226 | 0.78 | AAK1 (0.47) | AAK1NPC1RECQLRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903978-B1 | GDF-8 INHIBITORS | RIGEL PHARMACEUTICALS INC (US) | 2022-12-07 | — | — | EP | disclosed |