Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24718214 | 0.98 | EBP (0.36) | EBPSIGMAR1PDK1 | |
| SCHEMBL24717711 | 0.92 | EBP (0.35) | EBPSIGMAR1 | |
| SCHEMBL19822647 | 0.87 | EBP (0.41) | EBPSIGMAR1PDK1 | |
| SCHEMBL19822366 | 0.87 | EBP (0.41) | EBPSIGMAR1PDK1 | |
| SCHEMBL25682128 | 0.82 | EBP (0.39) | EBPSIGMAR1PDK1 | |
| SCHEMBL821790 | 0.82 | EBP (0.39) | EBPSIGMAR1PDK1 | |
| SCHEMBL25041958 | 0.82 | EBP (0.39) | EBPSIGMAR1PDK1 | |
| SCHEMBL25041962 | 0.82 | EBP (0.39) | EBPSIGMAR1PDK1 | |
| SCHEMBL24717719 | 0.82 | EBP (0.39) | EBPSIGMAR1PDK1 | |
| SCHEMBL23268148 | 0.80 | PDK1 (0.36) | EBPSIGMAR1PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220395576-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. | 2022-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220395576-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | BCL6, BCL6B, BCL3 | EBP 1750/4885SIGMAR1 4482/4885PDK1 2382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.