Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.35 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN4A | P35499 | 1/20 | 0.31 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25924736 | 0.88 | TSHR (0.57) | TSHRGBA1CYP2D6L3MBTL3L3MBTL1 | |
| SCHEMBL24717722 | 0.83 | TSHR (0.47) | TSHRCYP2D6L3MBTL3L3MBTL1CYP3A4 | |
| SCHEMBL29317112 | 0.79 | CYP2D6 (0.50) | TSHRGBA1CYP2D6CYP3A4ALDH1A1 | |
| SCHEMBL23588942 | 0.77 | SCN1A (0.36) | TSHRGBA1SIGMAR1SCN1ASCN4A | |
| SCHEMBL30121551 | 0.76 | GBA1 (0.39) | TSHRGBA1CYP2D6ARG1ARG2 | |
| SCHEMBL24267132 | 0.76 | GBA1 (0.36) | TSHRGBA1CYP2D6ARG1ARG2 | |
| SCHEMBL27268150 | 0.76 | TSHR (0.39) | TSHRGBA1CYP2D6CYP3A4ALDH1A1 | |
| SCHEMBL24717358 | 0.76 | CYP2D6 (0.36) | TSHRGBA1CYP2D6CYP3A4ALDH1A1 | |
| SCHEMBL25856124 | 0.76 | CYP2D6 (0.41) | TSHRCYP2D6CYP3A4ALDH1A1CYP2C19 | |
| SCHEMBL24267397 | 0.75 | GBA1 (0.36) | TSHRGBA1ARG1ARG2CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220395576-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. | 2022-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220395576-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | BCL6, BCL6B, BCL3 | TSHR 3100/4885GBA1 2636/4885CYP2D6 4179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.