Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | ARG1 | P05089 | 1/20 | 0.32 |
| ▸ | ARG2 | P78540 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24267132 | 0.92 | GBA1 (0.36) | GBA1TSHRGNAO1OPRM1OPRL1 | |
| SCHEMBL24866010 | 0.85 | GBA1 (0.36) | GBA1TSHRGNAO1OPRM1OPRL1 | |
| SCHEMBL24319374 | 0.85 | NCF1 (0.39) | TSHROPRM1OPRL1CACNA2D1CACNA1B | |
| SCHEMBL24481344 | 0.83 | GBA1 (0.37) | GBA1TSHRGNAO1OPRM1OPRL1 | |
| SCHEMBL27268150 | 0.79 | TSHR (0.39) | GBA1TSHRGNAO1CACNA2D1CACNA1B | |
| SCHEMBL24717358 | 0.79 | CYP2D6 (0.36) | GBA1TSHRKDM1AMAOBRCOR1 | |
| SCHEMBL24480580 | 0.78 | GNAO1 (0.34) | GBA1GNAO1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL22565135 | 0.78 | NCF1 (0.42) | TSHRGNAO1OPRM1OPRL1CACNA2D1 | |
| SCHEMBL24267159 | 0.77 | NCF1 (0.38) | TSHROPRM1OPRL1CACNA2D1CACNA1B | |
| SCHEMBL22564921 | 0.76 | TSHR (0.44) | GBA1TSHROPRM1OPRL1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3957633-A1 | A CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTORS AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2022-02-23 | — | — | EP | disclosed |