SCHEMBL24718795

SCHEMBL24718795

C=CC(=C)CCCCc1ccc(N(c2ccc(C)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 1/20 0.41
ALOX15 P16050 1/20 0.41
THRB P10828 7/20 0.40
THRA P10827 6/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
NAAA Q02083 1/20 0.36
CYP4Z1 Q86W10 1/20 0.35
LPL P06858 4/20 0.35
LIPG Q9Y5X9 4/20 0.35
HRH1 P35367 1/20 0.35
TRPV1 Q8NER1 1/20 0.34
MGLL Q99685 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12802074 0.86 IGF1R (0.44) IGF1RALOX15THRBTHRAMEN1
SCHEMBL31707487 0.82 THRB (0.44) IGF1RALOX15THRBTHRAMEN1
SCHEMBL15026002 0.80 IGF1R (0.52) IGF1RALOX15LPLLIPGHRH1
SCHEMBL14732512 0.80 IGF1R (0.52) IGF1RALOX15LPLLIPGHRH1
SCHEMBL10085713 0.80 CNR2 (0.37)
SCHEMBL12802534 0.79 CYP1A2 (0.43) IGF1RALOX15THRBTHRA
SCHEMBL15721715 0.79 IGF1R (0.50) IGF1RALOX15LPLLIPGHRH1
SCHEMBL22349600 0.79 IGF1R (0.50) IGF1RALOX15LPLLIPGHRH1
SCHEMBL28236265 0.79 IGF1R (0.50) IGF1RALOX15LPLLIPGHRH1
SCHEMBL14202419 0.79 IGF1R (0.50) IGF1RALOX15LPLLIPGHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3771736-B1 ELECTROCHROMIC ELEMENT RICOH CO LTD (JP) 2023-11-15 EP disclosed
EP-4063948-A1 ELECTROCHROMIC DISPLAY ELEMENT AND METHOD FOR PRODUCING ELECTROCHROMIC DISPLAY ELEMENT Ricoh Company, Ltd. (JP) 2022-09-28 EP disclosed