D-Glutamate

D-Glutamate

SCHEMBL2471979

C=CNC(CCC(=O)O)C(=O)O.NC(CCC(=O)O)C(=O)O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 2/20 0.60
GRM6 O15303 2/20 0.60
GRM7 Q14831 2/20 0.60
GRM4 Q14833 2/20 0.60
GRIN2D O15399 1/20 0.60
GRIN3B O60391 1/20 0.60
GSR P00390 1/20 0.60
CYP1A2 P05177 1/20 0.60
GRIK1 P39086 1/20 0.60
GRM5 P41594 1/20 0.60
GRIA1 P42261 1/20 0.60
GRIA2 P42262 1/20 0.60
GRIA3 P42263 1/20 0.60
SLC1A3 P43003 1/20 0.60
SLC1A2 P43004 1/20 0.60
SLC1A1 P43005 1/20 0.60
GRIA4 P48058 1/20 0.60
GRIN1 Q05586 1/20 0.60
GRIN2A Q12879 1/20 0.60
GRIK2 Q13002 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5089988 0.89 FOLH1 (0.55) GRM8GRM6GRM7GRM4GRIN2D
SCHEMBL5089992 0.89 FOLH1 (0.55) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL27762710 0.80 GRM8 (0.95) GRM8GRM6GRM7GRM4GRIN2D
Glutamic Acid SCHEMBL4607705 0.80 GRM8 (0.95) GRM8GRM6GRM7GRM4GRIN2D
Glutamic Acid SCHEMBL10355482 0.79 GRM8 (0.69) GRM8GRM6GRM7GRM4GRIN2D
SCHEMBL18680610 0.79 KMT2A (0.45) FOLH1BLMKMT2ARIMKLANAALAD2
D-Glutamate SCHEMBL9148962 0.78 GRM8 (0.75) GRM8GRM6GRM7GRM4GRIN2D
Glutamic Acid SCHEMBL9148975 0.78 GRM8 (0.75) GRM8GRM6GRM7GRM4GRIN2D
D-Glutamate SCHEMBL3661546 0.78 GRM8 (0.90) GRM8GRM6GRM7GRM4GRIN2D
Glutamic Acid SCHEMBL2683411 0.78 GRM8 (0.90) GRM8GRM6GRM7GRM4GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017189574-A1 METHOD FOR COLOURING HAIR INCLUDING PRETREATMENT NOXELL CORPORATION (US) 2017-11-02 WO disclosed
EP-2369948-A1 PRESERVATIVE SYSTEM FOR ACIDIC BEVERAGES BASED ON SEQUESTRANTS PepsiCo, Inc. (US) 2011-10-05 EP disclosed
WO-2010078069-A1 PRESERVATIVE SYSTEM FOR ACIDIC BEVERAGES BASED ON SEQUESTRANTS PEPSICO, INC. (US) 2010-07-08 WO disclosed
EP-1761966-A2 METHODS AND COMPOSITION FOR CLEANING AND PASSIVATING FUEL CELL SYSTEMS Honeywell International Inc. (US) 2007-03-14 EP disclosed
WO-2005108644-A2 METHODS AND COMPOSITION FOR CLEANING AND PASSIVATING FUEL CELL SYSTEMS HONEYWELL INTERNATIONAL INC. (US) 2005-11-17 WO disclosed