D-Glutamate

D-Glutamate

SCHEMBL3661546

C=C.NC(CCC(=O)O)C(=O)O

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM8 O00222 2/20 0.90
GRM6 O15303 2/20 0.90
GRM7 Q14831 2/20 0.90
GRM4 Q14833 2/20 0.90
GSR P00390 2/20 0.90
GRIN2D O15399 1/20 0.90
GRIN3B O60391 1/20 0.90
CYP1A2 P05177 1/20 0.90
GRIK1 P39086 1/20 0.90
GRM5 P41594 1/20 0.90
GRIA1 P42261 1/20 0.90
GRIA2 P42262 1/20 0.90
GRIA3 P42263 1/20 0.90
SLC1A3 P43003 1/20 0.90
SLC1A2 P43004 1/20 0.90
SLC1A1 P43005 1/20 0.90
GRIA4 P48058 1/20 0.90
GRIN1 Q05586 1/20 0.90
GRIN2A Q12879 1/20 0.90
GRIK2 Q13002 1/20 0.90

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamic Acid SCHEMBL2683411 1.00 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL19900160 1.00 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL8032706 0.98 GRM8 (0.86) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL26621747 0.95 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL26698369 0.95 GRM8 (0.90) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL1332297 0.95 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL17127348 0.95 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL1330824 0.95 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
D-Glutamate SCHEMBL1330484 0.95 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR
Glutamic Acid SCHEMBL5704264 0.95 GRM8 (1.00) GRM8GRM6GRM7GRM4GSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260033999-A1 TOPICAL APPLICATION FOR ABSORBENT ARTICLE PROCTER & GAMBLE (US) 2026-02-05 US disclosed
US-20250195281-A1 FLUID MANAGEMENT LAYER FOR AN ABSORBENT ARTICLE THE PROCTER & GAMBLE COMPANY 2025-06-19 US disclosed
US-20250195280-A1 FLUID MANAGEMENT LAYER FOR AN ABSORBENT ARTICLE THE PROCTER & GAMBLE COMPANY 2025-06-19 US disclosed
WO-2025128770-A1 FLUID MANAGEMENT LAYER FOR AN ABSORBENT ARTICLE THE PROCTER & GAMBLE COMPANY (US) 2025-06-19 WO disclosed
WO-2025128942-A1 FLUID MANAGEMENT LAYER FOR AN ABSORBENT ARTICLE THE PROCTER & GAMBLE COMPANY (US) 2025-06-19 WO disclosed
CN-118785877-A Topsheet system for absorbent article 宝洁公司 2024-10-15 CN disclosed
EP-4415668-A1 UPPER LAYER SYSTEM FOR ABSORBENT ARTICLE The Procter & Gamble Company (US) 2024-08-21 EP disclosed
CN-118076327-A Topsheet system for absorbent article 宝洁公司 2024-05-24 CN disclosed
US-20230277392-A1 UPPER LAYER SYSTEM FOR ABSORBENT ARTICLE THE PROCTER & GAMBLE COMPANY 2023-09-07 US disclosed
US-20230121636-A1 UPPER LAYER SYSTEM FOR ABSORBENT ARTICLE THE PROCTER & GAMBLE COMPANY 2023-04-20 US disclosed
WO-2023064746-A1 UPPER LAYER SYSTEM FOR ABSORBENT ARTICLE THE PROCTER & GAMBLE COMPANY (US) 2023-04-20 WO disclosed
EP-2242519-A2 ABSORBENT ARTICLE WITH LOTION COMPRISING A POLYPROPYLENE GLYCOL MATERIAL The Procter & Gamble Company (US) 2010-10-27 EP disclosed
EP-2117610-A2 ABSORBENT ARTICLE WITH LOTION COMPRISING A POLYPROPYLENE GLYCOL MATERIAL The Procter and Gamble Company (US) 2009-11-18 EP disclosed
WO-2009102837-A2 ABSORBENT ARTICLE WITH LOTION COMPRISING A POLYPROPYLENE GLYCOL MATERIAL THE PROCTER & GAMBLE COMPANY (US) 2009-08-20 WO disclosed
WO-2008101163-A2 ABSORBENT ARTICLE WITH LOTION COMPRISING A POLYPROPYLENE GLYCOL MATERIAL THE PROCTER & GAMBLE COMPANY (US) 2008-08-21 WO disclosed
CN-1420175-A High-tamp. resistant threonine synthetase gene, polypeptide coded therewith and preparing method thereof HUADA GENE RES & DEV CANTER HA (CN) 2003-05-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260033999-A1 TOPICAL APPLICATION FOR ABSORBENT ARTICLE SHBG, CUTA, PGF GRM8 4034/4885GRM6 4469/4885GRM7 3893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.