SCHEMBL2472223

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2476592	0.97	SYK (0.71)	SYKJAK3IRAK4JAK2JAK1
	SCHEMBL12301542	0.90	SYK (0.54)	SYKJAK3IRAK4JAK2JAK1
	SCHEMBL2475230	0.90	JAK3 (0.66)	SYKJAK3IRAK4JAK2JAK1
	SCHEMBL12206772	0.89	JAK3 (0.73)	SYKJAK3IRAK4JAK2JAK1
	SCHEMBL12301574	0.89	JAK3 (0.73)	SYKJAK3IRAK4JAK2JAK1
	SCHEMBL2484422	0.89	JAK3 (0.60)	SYKJAK3IRAK4JAK2JAK1
	SCHEMBL4409435	0.89	SYK (0.61)	SYKJAK3IRAK4JAK2JAK1
	SCHEMBL4406825	0.88	SYK (0.62)	SYKJAK3IRAK4JAK2JAK1
	SCHEMBL12301627	0.88	JAK3 (0.66)	SYKJAK3IRAK4JAK2JAK1
	SCHEMBL18916819	0.88	SYK (0.61)	SYKJAK3IRAK4JAK2JAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.