Trichloroacetic Acid

Trichloroacetic Acid

SCHEMBL2472230

CC(C)=O.O=C(O)C(Cl)(Cl)Cl

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.77
ALDH1A1 P00352 2/20 0.77
TP53 P04637 1/20 0.77
LMNA P02545 2/20 0.46
FFAR3 O14843 1/20 0.43
LCK P06239 1/20 0.43
FYN P06241 1/20 0.43
CA4 P22748 2/20 0.35
CYP1A2 P05177 1/20 0.33
THPO P40225 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
CA1 P00915 1/20 0.31
ALOX15 P16050 1/20 0.31
BLM P54132 1/20 0.31
PMP22 Q01453 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trichloroacetic Acid SCHEMBL3952041 0.92 TSHR (0.77) TSHRALDH1A1TP53LMNAFFAR3
Trichloroacetic Acid SCHEMBL8995195 0.88
Trichloroacetic Acid SCHEMBL3220 0.88
Trichloroacetic Acid SCHEMBL5311061 0.88 TSHR (1.00) TSHRALDH1A1TP53LMNAFFAR3
Trichloroacetic Acid SCHEMBL1331160 0.88
Trichloroacetic Acid SCHEMBL1331955 0.88
Trichloroacetic Acid SCHEMBL10745837 0.88
Trichloroacetic Acid SCHEMBL38661501 0.88
Trichloroacetic Acid SCHEMBL10493657 0.88 TSHR (1.00) TSHRALDH1A1TP53LMNAFFAR3
Trichloroacetic Acid SCHEMBL28929866 0.85 ALDH1A1 (0.56) TSHRALDH1A1TP53LMNAFFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114736861-B Mononuclear or macrophage loaded with immune checkpoint nano antibody attenuated salmonella and preparation method and application thereof 江苏靶标生物医药研究所有限公司 2024-05-28 CN claimed
CN-114736861-A Mononuclear or macrophage loaded with salmonella attenuated by secreting and expressing immune checkpoint nano antibody and preparation method and application thereof 江苏靶标生物医药研究所有限公司 2022-07-12 CN claimed
CN-107192829-A A kind of method of Radix Isatidis identification of proteins 南京中医药大学 2017-09-22 CN claimed
CN-106754584-A For the Lactobacillus plantarum SWUN5815 of bacteriocinogeny high and its application 西南民族大学 2017-05-31 CN claimed
CN-103411809-B A kind of normal temperature preserves the method for Procambius clarkii each tissue protein group protein sample Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences (CN) 2016-02-10 CN claimed
CN-103330719-B A kind of kangaroo bone extract and extracting method thereof NANJING YOUER BIOTECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2015-08-05 CN claimed
CN-103411809-A Normal-temperature preservation method of procambarus clarkia tissue proteomics protein samples FW FISHERIES RES CT CAFS 2013-11-27 CN claimed
CN-103330719-A Kangaroo bone extract and extraction method thereof NANJING YOUER BIOTECHNOLOGY DEV CO LTD 2013-10-02 CN claimed
CN-102721730-A Method for obtaining two-dimensional electrophoresis patterns of proteins of gonads of stichopus japonicus by two-dimensional electrophoresis technology UNIV DALIAN OCEAN 2012-10-10 CN claimed
CN-101329300-A Construction and application of cardiac muscle cell protein difference expression atlas UNIV ZHEJIANG (CN) 2008-12-24 CN claimed
JP-8183798-A None JP disclosed
CN-114480463-B Novel coronavirus vaccine antigen presentation system for secreting and expressing RBD structural domain protein by attenuated salmonella and application thereof 南京吉芮康生物科技研究院有限公司 2024-07-16 CN disclosed
CN-114736861-B Mononuclear or macrophage loaded with immune checkpoint nano antibody attenuated salmonella and preparation method and application thereof 江苏靶标生物医药研究所有限公司 2024-05-28 CN disclosed
CN-114478715-B Novel coronavirus vaccine presentation system for attenuated salmonella secretion expression of S2 structural domain protein and application thereof 南京吉芮康生物科技研究院有限公司 2023-12-22 CN disclosed
US-20230383259-A1 IN VIVO ADIPOSE BIOREACTOR AND KITS FOR THE PRODUCTION AND DELIVERY OF BIOLOGIC AGENTS THE BRIGHAM AND WOMEN'S HOSPITAL, INC. 2023-11-30 US disclosed
US-20030087410-A1 Nicotianamine synthase and gene encoding the same JAPAN SCIENCE AND TECHNOLOGY CORPORATION 2003-05-08 US disclosed
EP-1077255-A1 NICOTIANAMINE SYNTHASE AND GENE ENCODING THE SAME Japan Science and Technology Corporation (JP) 2001-02-21 EP disclosed
US-5670629-A RESOLUTION AGENT SHINWA CHEMICAL INDUSTRIES, LTD. (JP) 1997-09-23 US disclosed
JP-H08183798-A OVOGLYCOPROTEIN, CHROMATOGRAPHIC SEPARATION AGENT CONTAINING THE COMPOUND AND SEPARATION METHOD SHINWA KAKO KK 1996-07-16 JP disclosed
US-4112074-A POSTOVALBUMIN, PROTEIN Y TRUFFIER JEAN CLAUDE 1978-09-05 US disclosed