Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 8/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 8/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23198481 | 0.85 | PDCD1 (0.47) | PDCD1CD274 | |
| SCHEMBL23201568 | 0.79 | PDCD1 (0.40) | PDCD1CD274 | |
| SCHEMBL23201345 | 0.78 | PDCD1 (0.47) | PDCD1CD274 | |
| SCHEMBL23201522 | 0.72 | PRMT5 (0.45) | PDCD1CD274 | |
| SCHEMBL23202563 | 0.70 | PDCD1 (0.55) | PDCD1CD274 | |
| SCHEMBL23202675 | 0.70 | PDCD1 (0.41) | PDCD1CD274 | |
| SCHEMBL23198918 | 0.67 | GRM2 (0.34) | — | |
| SCHEMBL23198483 | 0.67 | GRM2 (0.35) | — | |
| SCHEMBL23198440 | 0.65 | GRM2 (0.35) | — | |
| SCHEMBL23199858 | 0.62 | PDCD1 (0.62) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4043461-A1 | COMPOUND AS SMALL MOLECULE INHIBITOR PD-1/PD-L1 AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2022-08-17 | — | — | EP | disclosed |