Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25070943 | 0.76 | DDB1 (0.38) | DDB1CRBNIRAK4 | |
| SCHEMBL30617431 | 0.76 | DDB1 (0.38) | DDB1CRBNIRAK4 | |
| SCHEMBL23200203 | 0.76 | AAK1 (0.38) | USP30 | |
| SCHEMBL28903468 | 0.75 | DDB1 (0.35) | DDB1CRBNIRAK4 | |
| SCHEMBL38664462 | 0.74 | DDB1 (0.34) | DDB1CRBNIRAK4 | |
| SCHEMBL25664268 | 0.74 | DDB1 (0.34) | DDB1CRBNIRAK4 | |
| SCHEMBL24687471 | 0.72 | DDB1 (0.33) | DDB1CRBNIRAK4 | |
| SCHEMBL26024955 | 0.72 | USP30 (0.37) | USP30 | |
| SCHEMBL29984176 | 0.71 | PRMT5 (0.38) | USP30 | |
| SCHEMBL29983594 | 0.71 | PRMT5 (0.38) | USP30IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4043461-A1 | COMPOUND AS SMALL MOLECULE INHIBITOR PD-1/PD-L1 AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2022-08-17 | — | — | EP | disclosed |