Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21356696 | 0.78 | AKT1 (0.43) | USP30HDAC1HDAC2 | |
| SCHEMBL22796372 | 0.77 | USP30 (0.39) | USP30HDAC6HDAC1HDAC2BACE1 | |
| SCHEMBL24722595 | 0.72 | DDB1 (0.33) | USP30 | |
| SCHEMBL1316483 | 0.71 | USP30 (0.39) | USP30HDAC1HDAC2BACE1BACE2 | |
| SCHEMBL21626233 | 0.70 | USP30 (0.37) | USP30HDAC6HDAC1HDAC2BACE1 | |
| SCHEMBL16665221 | 0.69 | USP30 (0.33) | USP30HDAC6 | |
| SCHEMBL18761829 | 0.68 | USP30 (0.32) | USP30 | |
| SCHEMBL2595119 | 0.67 | AAK1 (0.45) | USP30BACE1BACE2AAK1 | |
| SCHEMBL22035790 | 0.66 | USP30 (0.34) | USP30BACE1BACE2AAK1 | |
| SCHEMBL1962792 | 0.65 | MEN1 (0.45) | HDAC6HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |