Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | NNMT | P40261 | 2/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24723535 | 0.82 | SMYD3 (0.36) | SMYD3DDB1CRBNNNMT | |
| SCHEMBL24723078 | 0.79 | SMYD3 (0.36) | SMYD3DDB1CRBNNNMTIDH1 | |
| SCHEMBL24722620 | 0.78 | DDB1 (0.35) | SMYD3DDB1CRBNNNMT | |
| SCHEMBL10257795 | 0.77 | CRBN (0.48) | CRBN | |
| SCHEMBL24722681 | 0.74 | GAA (0.41) | DDB1CRBN | |
| SCHEMBL24722680 | 0.73 | NNMT (0.32) | SMYD3NNMT | |
| SCHEMBL11916074 | 0.72 | ABL1 (0.54) | SMYD3CRBN | |
| SCHEMBL15910099 | 0.71 | MB (0.32) | — | |
| SCHEMBL13658077 | 0.71 | KMT2A (0.36) | CRBN | |
| SCHEMBL12892808 | 0.71 | CRBN (0.31) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022187329-A1 | FABI INHIBITORS FOR GRAM-NEGATIVE PATHOGENS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2022-09-09 | — | — | WO | disclosed |