Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 8/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | HTR2B | P41595 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29993190 | 0.87 | HTR6 (0.61) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL24723312 | 0.87 | HTR6 (0.61) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL24043693 | 0.85 | KMT2A (0.43) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL29992742 | 0.84 | HTR6 (0.51) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL4225666 | 0.82 | HTR6 (0.70) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL29400156 | 0.82 | HTR6 (0.70) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL29394272 | 0.80 | HTR6 (0.53) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL30374467 | 0.80 | HTR2A (0.55) | MTNR1AMTNR1BHTR2AHTR2CHTR2B | |
| SCHEMBL24723326 | 0.80 | GAA (0.68) | HTR2AHTR2CHTR2BHTR1AHTR6 | |
| SCHEMBL20970924 | 0.79 | HTR6 (0.55) | MTNR1AMTNR1BHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022232931-A1 | CATALYTIC TRYPTAMINE PROCESSES AND PRECURSORS | KARE CHEMICAL TECHNOLOGIES INC. (CA) | 2022-11-10 | — | — | WO | disclosed |