Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 3/20 | 0.58 |
| ▸ | PYGM | P11217 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24683905 | 0.81 | MAOB (0.55) | MTNR1BPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL1341786 | 0.81 | TSHR (0.58) | KDM4EPOLBL3MBTL1MAPTNPSR1 | |
| SCHEMBL13791510 | 0.80 | MAPK1 (0.65) | MTNR1BKDM4EPOLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL26270864 | 0.77 | MTNR1B (0.73) | MTNR1BPYGMKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL6240378 | 0.77 | APP (0.48) | KDM4EPOLBSMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL26218878 | 0.77 | MEN1 (0.56) | MTNR1BPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5609585 | 0.77 | AR (0.55) | MTNR1BKDM4EPOLBSMN1; SMN2MEN1 | |
| SCHEMBL8145865 | 0.76 | MTNR1B (0.65) | MTNR1BPYGMPOLBMEN1KMT2A | |
| SCHEMBL25386995 | 0.75 | MTNR1B (0.75) | MTNR1BPYGMKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL5537634 | 0.75 | KDM4E (0.49) | MTNR1BKDM4EPOLBSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022232509-A1 | PCNA INHIBITORS AND EGFR INHIBITORS FOR CANCER TREATMENT | CITY OF HOPE (US) | 2022-11-03 | — | — | WO | disclosed |