SCHEMBL24725154

SCHEMBL24725154

N=C(N)NCCC[C@H](N)C(=O)N[C@H](C=O)Cc1cnc[nH]1

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.43
SLC7A5 Q01650 1/20 0.43
NLN Q9BYT8 2/20 0.41
SLC15A2 Q16348 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21828571 0.84 SLC15A2 (0.52) CYP3A4SLC7A5SLC15A2
SCHEMBL12581260 0.84 SLC15A2 (0.42) SLC15A2
SCHEMBL27687361 0.82 SLC15A2 (0.54) CYP3A4SLC7A5NLNSLC15A2
SCHEMBL12581296 0.80 SLC15A2 (0.42) SLC15A2
Arginine SCHEMBL28235438 0.80 CYP3A4 (0.64) CYP3A4SLC7A5NLN
SCHEMBL26312334 0.80 SLC15A2 (0.64) CYP3A4SLC7A5SLC15A2
SCHEMBL1537334 0.79 CYP3A4 (0.49) CYP3A4SLC7A5NLN
SCHEMBL176373 0.79 CYP3A4 (0.49) CYP3A4SLC7A5NLN
SCHEMBL16421633 0.78 NPY4R (0.41)
SCHEMBL27687339 0.77 SLC15A2 (0.63) CYP3A4SLC7A5SLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022235699-A2 POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS AVILAR THERAPEUTICS, INC. (US) 2022-11-10 WO disclosed