SCHEMBL176373

SCHEMBL176373

N=C(N)NCCC[C@H](N)C(=O)OC(=O)[C@@H](N)Cc1cnc[nH]1

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.49
SLC7A5 Q01650 1/20 0.49
NLN Q9BYT8 2/20 0.47
HRH3 Q9Y5N1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1537334 1.00 CYP3A4 (0.49) CYP3A4SLC7A5NLNHRH3
SCHEMBL17113854 0.87 CYP3A4 (0.38) CYP3A4SLC7A5NLNHRH3
Arginine SCHEMBL28235438 0.85 CYP3A4 (0.64) CYP3A4SLC7A5NLN
SCHEMBL1537239 0.82 CPB2 (0.60) CYP3A4SLC7A5HRH3
SCHEMBL1537285 0.82 CYP3A4 (0.71) CYP3A4SLC7A5HRH3
SCHEMBL163444 0.82 CYP3A4 (0.71) CYP3A4SLC7A5HRH3
SCHEMBL305857 0.81 CYP3A4 (0.56) CYP3A4SLC7A5HRH3
SCHEMBL902056 0.81 CYP3A4 (0.56) CYP3A4SLC7A5HRH3
SCHEMBL5221763 0.80 CYP3A4 (0.65) CYP3A4SLC7A5HRH3
Hydrochloric Acid SCHEMBL28331180 0.80 CYP3A4 (0.69) CYP3A4SLC7A5HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115716871-A Method for inactivating viral contaminants 伊克诺斯科学公司 2023-02-28 CN claimed
US-20220112237-A1 AMINO ACID COMPOSITION HAVING CO-AMORPHOUS STRUCTURE AJINOMOTO CO., INC. (JP) 2022-04-14 US claimed
CN-111050799-A Method for inactivating viral contaminants 伊克诺斯科学公司 2020-04-21 CN claimed
EP-3245296-A1 IN VITRO METHOD FOR ESTIMATING IN VIVO PROTEIN DIGESTIBILITY General Mills, Inc. (US) 2017-11-22 EP claimed
WO-2016115249-A1 IN VITRO METHOD FOR ESTIMATING IN VIVO PROTEIN DIGESTIBILITY GENERAL MILLS, INC. (US) 2016-07-21 WO claimed
CN-105431167-A Non-naturally occurring factor h binding proteins (FHBP) and methods of use thereof CHILDREN'S HOSPITAL & RES CENTER OAKLAND 2016-03-23 CN claimed
US-8981053-B2 Molecules specifically binding pancreatic beta cells biomarkers UNIVERSITE DE MONS (BE) 2015-03-17 US claimed
CN-104043101-A Icatibant composition for injection and preparation method and preparation thereof HANGZHOU SINOPEP PHARMACEUTICAL INC 2014-09-17 CN claimed
EP-1481052-B1 HYALURONAN SYNTHASE GENES AND EXPRESSION THEREOF UNIV OKLAHOMA STATE (US) 2010-06-09 EP claimed
JP-2009529509-A 2009-08-20 JP claimed
EP-2007791-A2 MODIFIED MOLECULES WHICH PROMOTE HEMATOPOIESIS AplaGen GmbH (DE) 2008-12-31 EP claimed
WO-2007101698-A2 MODIFIED MOLECULES WHICH PROMOTE HEMATOPOIESIS APLAGEN GMBH (DE) 2007-09-13 WO claimed
EP-0523189-B1 CATIONIC LIPIDS FOR INTRACELLULAR DELIVERY OF BIOLOGICALLY ACTIVE MOLECULES VICAL INC (US) 1999-06-16 EP claimed
EP-0717753-A1 RIBOSOME INACTIVATING PROTEINS EXTRACTED FROM SEEDS OF SAPONARIA OCYMOIDES AND VACCARIA PYRAMIDATA, THEIR PREPARATION AND IMMUNOTOXINS CONTAINING THEM Menarini Ricerche S.p.A. (IT) 1996-06-26 EP claimed
WO-1995007297-A1 RIBOSOME INACTIVATING PROTEINS EXTRACTED FROM SEEDS OF SAPONARIA OCYMOIDES AND VACCARIA PYRAMIDATA, THEIR PREPARATION AND IMMUNOTOXINS CONTAINING THEM MENARINI RICERCHE SUD S.P.A. (IT) 1995-03-16 WO claimed
EP-0175871-B1 PROCESS FOR IMPROVING OR MODIFYING THE TASTE AND AROMA OF CITRUS FRUIT COMPOSITIONS FIRMENICH SA (CH) 1988-03-23 EP claimed
EP-0175871-A1 Process for improving or modifying the taste and aroma of citrus fruit compositions FIRMENICH SA (CH) 1986-04-02 EP claimed
US-20240190985-A1 THERAPEUTIC CD99 ANTIBODIES NEW YORK UNIVERSITY 2024-06-13 US disclosed
WO-1988006035-A1 OMEGA-3 FATTY ACIDS IN TRAUMATIC INJURY TREATMENT SHRINERS HOSPITALS FOR CRIPPLED CHILDREN (US) 1988-08-25 WO disclosed
EP-0175871-A1 Process for improving or modifying the taste and aroma of citrus fruit compositions FIRMENICH SA (CH) 1986-04-02 EP disclosed