SCHEMBL24725161

SCHEMBL24725161

CC1(C)O[C@@H]2[C@@H](NC(=O)C(F)(F)F)[C@H]3OC[C@](C)(O3)[C@@H]2O1

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ASGR1 P07306 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17273230 0.84 ASGR1 (0.43) ASGR1
SCHEMBL23346073 0.83 ASGR1 (0.62) ASGR1
SCHEMBL26698324 0.77 ASGR1 (0.64) ASGR1
SCHEMBL26888865 0.77 ASGR1 (0.64) ASGR1
SCHEMBL25867163 0.77 ASGR1 (0.64) ASGR1
SCHEMBL26879967 0.76 ASGR1 (0.46) ASGR1
SCHEMBL24725172 0.75 ASGR1 (0.44) ASGR1
SCHEMBL21479785 0.75 ASGR1 (0.44) ASGR1
SCHEMBL30063862 0.75 ASGR1 (0.44) ASGR1
SCHEMBL21479699 0.71 ASGR1 (0.42) ASGR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022235699-A2 POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS AVILAR THERAPEUTICS, INC. (US) 2022-11-10 — — WO disclosed
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