Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASGR1 | P07306 | 4/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24725115 | 0.97 | ASGR1 (0.35) | ASGR1HCRTR1HCRTR2IDH1 | |
| SCHEMBL24725099 | 0.82 | MALT1 (0.39) | ASGR1KCNH2 | |
| SCHEMBL24725263 | 0.81 | ASGR1 (0.52) | ASGR1HCRTR1HCRTR2 | |
| SCHEMBL30063180 | 0.81 | ASGR1 (0.52) | ASGR1HCRTR1HCRTR2 | |
| SCHEMBL24725421 | 0.76 | ASGR1 (0.33) | ASGR1 | |
| SCHEMBL24725425 | 0.76 | MALT1 (0.40) | ASGR1KCNH2 | |
| SCHEMBL24725141 | 0.76 | ASGR1 (0.33) | ASGR1 | |
| SCHEMBL24724816 | 0.75 | ASGR1 (0.33) | ASGR1 | |
| SCHEMBL24724877 | 0.74 | HCRTR1 (0.34) | HCRTR1HCRTR2IDH1 | |
| SCHEMBL31376879 | 0.74 | ASGR1 (0.46) | ASGR1HCRTR1HCRTR2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235699-A2 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |