SCHEMBL24724816

SCHEMBL24724816

COc1cc(N[C@H]2[C@H]3OC[C@](CC4CC(CCC5CCC(CC6CCC6)C5)C4)(O3)[C@H](O)[C@@H]2O)nc(C(F)(F)F)n1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ASGR1 P07306 6/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30064584 0.81 ASGR1 (0.47) ASGR1
SCHEMBL27180318 0.81 ASGR1 (0.47) ASGR1
SCHEMBL24725099 0.80 MALT1 (0.39) ASGR1
SCHEMBL24725425 0.80 MALT1 (0.40) ASGR1
SCHEMBL24725115 0.76 ASGR1 (0.35) ASGR1
SCHEMBL24725419 0.75 ASGR1 (0.34) ASGR1
SCHEMBL24725424 0.70 MALT1 (0.37) —
SCHEMBL24725113 0.69 MALT1 (0.39) —
SCHEMBL24725421 0.69 ASGR1 (0.33) ASGR1
SCHEMBL24725141 0.68 ASGR1 (0.33) ASGR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022235699-A2 POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS AVILAR THERAPEUTICS, INC. (US) 2022-11-10 — — WO disclosed
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