Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 7/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.50 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20475319 | 0.89 | HPGD (0.53) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL24725921 | 0.86 | ALDH1A1 (0.55) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL24725849 | 0.86 | HPGD (0.59) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL24725850 | 0.85 | HPGD (0.55) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL24725913 | 0.84 | HPGD (0.58) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL24725846 | 0.82 | PDE4A (0.40) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL24725920 | 0.82 | GRIN1 (0.43) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL28658600 | 0.80 | HPGD (0.81) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL2945938 | 0.79 | TSHR (0.42) | HPGDTSHRPDE4APDE4BPDE4C | |
| SCHEMBL663026 | 0.77 | CYP19A1 (0.40) | HPGDTSHRPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11518754-B2 | Radiolabeled pharmaceuticals and methods of making and using same | YALE UNIVERSITY (US) | 2022-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11518754-B2 | Radiolabeled pharmaceuticals and methods of making and using same | SLC18A2, SLC18A3, SLC1A2 | HPGD 4122/4885TSHR 1884/4885PDE4A 1033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.