SCHEMBL24725980

SCHEMBL24725980

CCS(=O)(=O)c1cc2ccccc2nc1C(=O)Nc1ccc(C(F)(F)F)cn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 2/20 0.47
GAA P10253 1/20 0.45
CNR1 P21554 2/20 0.45
CNR2 P34972 2/20 0.45
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
PTGS1 P23219 1/20 0.45
FGFR4 P22455 2/20 0.43
MAPKAPK2 P49137 1/20 0.43
PTGES O14684 1/20 0.43
NPY5R Q15761 1/20 0.42
SCN9A Q15858 2/20 0.42
DYRK1A Q13627 1/20 0.41
TRPV1 Q8NER1 1/20 0.41
DEGS1 O15121 1/20 0.41
HCRTR1 O43613 1/20 0.40
TP53 P04637 1/20 0.40
MAPT P10636 1/20 0.40
NFKB1 P19838 1/20 0.40
NFKB2 Q00653 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16762185 0.84 PTGS1 (0.51) GAANPC1RAB9APTGS1FGFR4
SCHEMBL24725972 0.82 FGFR4 (0.46) PPARDGAANPC1RAB9APTGS1
SCHEMBL16872874 0.80 TRPV1 (0.52) PPARDGAANPC1RAB9APTGS1
SCHEMBL16891372 0.80 PTGS1 (0.46) GAACNR1NPC1RAB9APTGS1
SCHEMBL24725971 0.79 GAA (0.46) PPARDGAANPC1RAB9APTGS1
SCHEMBL16885474 0.77 MEN1 (0.48) GAACNR1NPC1RAB9APTGS1
SCHEMBL19437675 0.75 ALDH1A1 (0.50) GAANPC1RAB9AMAPTSMN1; SMN2
SCHEMBL24726015 0.75 NPY5R (0.43) GAACNR1CNR2NPC1RAB9A
SCHEMBL24726387 0.74 PPARD (0.46) PPARDGAACNR1PTGS1NPY5R
SCHEMBL31239007 0.74 PPARD (0.46) PPARDGAACNR1PTGS1NPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022259985-A1 PEST CONTROLLING AGENT 日本化薬株式会社 2022-12-15 WO disclosed