SCHEMBL24726460

SCHEMBL24726460

CC(C)c1cc(F)cc(Oc2cccc(CC(C)c3cccc(Oc4cc(F)cc(F)c4)c3)c2)c1

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FDFT1 P37268 5/20 0.45
RORC P51449 1/20 0.40
TAAR1 Q96RJ0 2/20 0.38
CETP P11597 3/20 0.38
PTGS1 P23219 1/20 0.36
FFAR1 O14842 2/20 0.34
FFAR4 Q5NUL3 1/20 0.34
ADRB1 P08588 1/20 0.34
ADRB3 P13945 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22001033 0.83 PTGS1 (0.45) FDFT1RORCCETPPTGS1FFAR1
SCHEMBL19317583 0.80 PTGS1 (0.41) FDFT1RORCPTGS1FFAR1FFAR4
SCHEMBL30520177 0.78 MAOB (0.50) FDFT1TAAR1PTGS1
SCHEMBL19317577 0.74 PTGS1 (0.47) FDFT1PTGS1
SCHEMBL25381888 0.74 FDFT1 (0.53) FDFT1TAAR1CETPPTGS1FFAR1
SCHEMBL24726464 0.73 TAAR1 (0.47) FDFT1TAAR1CETP
SCHEMBL25530101 0.73 KDM4E (0.40) TAAR1CETP
SCHEMBL16301354 0.73 FDFT1 (0.46) FDFT1CETPFFAR1FFAR4
SCHEMBL27428302 0.72 PLG (0.37) FDFT1TAAR1CETPFFAR1
SCHEMBL14040984 0.71 KDM4E (0.49) RORCTAAR1CETPPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022234965-A1 HETEROARYL DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT 주식회사 보로노이 2022-11-10 WO disclosed