SCHEMBL24726464

SCHEMBL24726464

CC(C)Cc1cccc(Oc2cccc(F)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.47
PPARG P37231 1/20 0.47
PPARA Q07869 1/20 0.47
CETP P11597 3/20 0.45
FDFT1 P37268 2/20 0.45
MAOB P27338 2/20 0.43
HPGD P15428 1/20 0.40
MRGPRX4 Q96LA9 1/20 0.40
IDO1 P14902 1/20 0.40
AGXT P21549 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9538055 0.89 TAAR1 (0.56) TAAR1PPARGPPARACETPFDFT1
SCHEMBL8171976 0.89 CETP (0.47) TAAR1PPARGPPARACETPFDFT1
SCHEMBL8174800 0.84 CETP (0.54) TAAR1PPARGPPARACETPFDFT1
SCHEMBL8172098 0.84 FDFT1 (0.47) TAAR1PPARGPPARACETPFDFT1
SCHEMBL2623871 0.84 TAAR1 (0.50) TAAR1MAOBIDO1AGXT
SCHEMBL16301334 0.81 MAOB (0.46) PPARGPPARACETPFDFT1MAOB
SCHEMBL13718948 0.80 FFAR1 (0.48) TAAR1PPARGPPARACETPFDFT1
SCHEMBL13718717 0.80 TAAR1 (0.60) TAAR1CETPMAOBIDO1AGXT
SCHEMBL13718930 0.80 TAAR1 (0.60) TAAR1PPARGPPARACETPIDO1
SCHEMBL8252058 0.80 FDFT1 (0.49) TAAR1PPARGPPARACETPFDFT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022234965-A1 HETEROARYL DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT 주식회사 보로노이 2022-11-10 WO disclosed