Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.56 |
| ▸ | CETP | P11597 | 1/20 | 0.48 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8174800 | 0.94 | CETP (0.54) | TAAR1CETPFDFT1PTGESMME | |
| SCHEMBL13718717 | 0.89 | TAAR1 (0.60) | TAAR1CETPKDM4EALDH1A1HTT | |
| SCHEMBL13718930 | 0.89 | TAAR1 (0.60) | TAAR1CETPPPARGPPARAKDM4E | |
| SCHEMBL24726464 | 0.89 | TAAR1 (0.47) | TAAR1CETPFDFT1PPARGPPARA | |
| SCHEMBL13718948 | 0.89 | FFAR1 (0.48) | TAAR1CETPFDFT1PTGESMME | |
| SCHEMBL8171976 | 0.88 | CETP (0.47) | TAAR1CETPFDFT1PTGESPPARG | |
| SCHEMBL13719005 | 0.88 | TAAR1 (0.46) | TAAR1CETPFDFT1PPARGPPARA | |
| SCHEMBL13719088 | 0.88 | PPARG (0.59) | TAAR1CETPFDFT1PPARGPPARA | |
| SCHEMBL8172098 | 0.87 | FDFT1 (0.47) | TAAR1CETPFDFT1PTGESMME | |
| SCHEMBL13719216 | 0.87 | KMO (0.48) | TAAR1CETPFDFT1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003012-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-18 | — | — | WO | disclosed |