Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.54 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.53 |
| ▸ | IGF1R | P08069 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | CTSC | P53634 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21816616 | 0.88 | EGFR (0.59) | EGFRUCHL3IGF1RKCNH2 | |
| SCHEMBL31348830 | 0.87 | EGFR (0.53) | EGFRUCHL3IGF1RKCNH2 | |
| SCHEMBL16385655 | 0.87 | EGFR (0.53) | EGFRUCHL3IGF1RKCNH2 | |
| SCHEMBL21557759 | 0.86 | EGFR (0.49) | EGFR | |
| SCHEMBL21816701 | 0.84 | EGFR (0.54) | EGFRUCHL3IGF1RKCNH2 | |
| SCHEMBL23983216 | 0.84 | EGFR (0.55) | EGFRIGF1RKCNH2 | |
| SCHEMBL16385654 | 0.83 | EGFR (0.50) | EGFRUCHL3IGF1RKCNH2 | |
| SCHEMBL19221921 | 0.82 | EGFR (0.53) | EGFRIGF1RKCNH2 | |
| SCHEMBL29823131 | 0.82 | EGFR (0.53) | EGFRIGF1RKCNH2 | |
| SCHEMBL18902049 | 0.82 | EGFR (0.53) | EGFRIGF1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234965-A1 | HETEROARYL DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 보로노이 | 2022-11-10 | — | — | WO | disclosed |