Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.53 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.52 |
| ▸ | IGF1R | P08069 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16385655 | 1.00 | EGFR (0.53) | EGFRUCHL3IGF1RKCNH2 | |
| SCHEMBL19027792 | 0.90 | EGFR (0.47) | EGFRIGF1RKCNH2 | |
| SCHEMBL19027789 | 0.90 | EGFR (0.47) | EGFRIGF1RKCNH2 | |
| SCHEMBL19089377 | 0.88 | BRPF1 (0.47) | EGFRIGF1RKCNH2 | |
| SCHEMBL19089376 | 0.88 | EGFR (0.46) | EGFRIGF1RKCNH2 | |
| SCHEMBL25350305 | 0.87 | EGFR (0.49) | EGFRIGF1RKCNH2 | |
| SCHEMBL20680878 | 0.87 | EGFR (0.51) | EGFR | |
| SCHEMBL21949622 | 0.87 | EGFR (0.45) | EGFRIGF1RKCNH2 | |
| SCHEMBL24726489 | 0.87 | EGFR (0.54) | EGFRUCHL3IGF1RKCNH2 | |
| SCHEMBL19027961 | 0.86 | EGFR (0.45) | EGFRIGF1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119591551-A | 2, 4-Diaryl amino pyrimidine analogue, and preparation method and application thereof | 沈阳药科大学 | 2025-03-11 | — | — | CN | disclosed |