Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24726642 | 0.81 | MAPK1 (0.41) | TGFBR1MAPK14RXRARXRBRXRG | |
| SCHEMBL12609895 | 0.76 | DYRK1A (0.60) | DYRK1ATGFBR1MAPK14SCN5APIK3CD | |
| SCHEMBL84387 | 0.76 | DYRK1A (0.44) | DYRK1ATGFBR1MAPK14SCN5ATLR9 | |
| SCHEMBL30014450 | 0.74 | DYRK1A (0.51) | DYRK1ATGFBR1MAPK14SCN5APIK3CD | |
| SCHEMBL30013771 | 0.74 | EGLN2 (0.58) | DYRK1ATGFBR1MAPK14SCN5A | |
| SCHEMBL749404 | 0.74 | DYRK1A (0.51) | DYRK1ATGFBR1MAPK14SCN5APIK3CD | |
| SCHEMBL938164 | 0.73 | DYRK1A (0.50) | DYRK1ATGFBR1MAPK14SCN5APIK3CD | |
| SCHEMBL30013812 | 0.72 | DYRK1A (0.49) | DYRK1ATGFBR1MAPK14SCN5APIK3CD | |
| SCHEMBL30014288 | 0.72 | DYRK1A (0.49) | DYRK1ATGFBR1MAPK14SCN5APIK3CD | |
| SCHEMBL5352034 | 0.72 | RXRA (0.62) | RXRARXRBRXRGPTPN5NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234965-A1 | HETEROARYL DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 보로노이 | 2022-11-10 | — | — | WO | disclosed |