Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | GAK | O14976 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31457017 | 0.83 | KCNH2 (0.41) | PRMT6LOXL2PDGFRBPDGFRACYP17A1 | |
| SCHEMBL27375492 | 0.83 | KCNH2 (0.41) | PRMT6LOXL2PDGFRBPDGFRACYP17A1 | |
| SCHEMBL3235807 | 0.81 | CYP2A6 (0.50) | PRMT6PDGFRBPDGFRACYP17A1CYP11B1 | |
| SCHEMBL30340237 | 0.75 | PRMT6 (0.68) | PRMT6LOXL2CYP2A6CYP2E1CYP2B6 | |
| SCHEMBL10162041 | 0.75 | PRMT6 (0.68) | PRMT6LOXL2CYP2A6CYP2E1CYP2B6 | |
| SCHEMBL5023933 | 0.74 | CYP17A1 (0.56) | PRMT6CYP17A1CYP11B1CYP2A6CYP2E1 | |
| SCHEMBL21944861 | 0.73 | ERN1 (0.49) | PDGFRBPDGFRACYP2A6ERN1CYP2E1 | |
| SCHEMBL13992542 | 0.73 | CYP17A1 (0.46) | CYP17A1CYP11B1CYP21A2RXRARXRB | |
| SCHEMBL4886445 | 0.73 | CYP2A6 (0.53) | PDGFRBPDGFRACYP17A1CYP11B1CYP21A2 | |
| SCHEMBL30751360 | 0.71 | GRM2 (0.42) | PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234965-A1 | HETEROARYL DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 보로노이 | 2022-11-10 | — | — | WO | disclosed |