Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 14/20 | 0.86 |
| ▸ | AURKA | O14965 | 1/20 | 0.86 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.86 |
| ▸ | NEK2 | P51955 | 1/20 | 0.68 |
| ▸ | PTK2 | Q05397 | 5/20 | 0.64 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21446913 | 0.92 | AXL (0.87) | AXLAURKAAURKBNEK2PTK2 | |
| Dubermatinib SCHEMBL29394359 | 0.92 | AXL (1.00) | AXLAURKAAURKBNEK2PTK2 | |
| Dubermatinib SCHEMBL12813478 | 0.92 | AXL (1.00) | AXLAURKAAURKBNEK2PTK2 | |
| SCHEMBL21446896 | 0.90 | AXL (0.83) | AXLAURKAAURKBNEK2PTK2 | |
| SCHEMBL22872062 | 0.88 | AXL (0.79) | AXLAURKAAURKBNEK2PTK2 | |
| SCHEMBL22872061 | 0.88 | AXL (0.79) | AXLAURKAAURKBNEK2PTK2 | |
| Dubermatinib SCHEMBL29814405 | 0.86 | AXL (0.87) | AXLAURKAAURKBNEK2PTK2 | |
| Dubermatinib SCHEMBL29814119 | 0.86 | AXL (0.87) | AXLAURKAAURKBNEK2PTK2 | |
| SCHEMBL21446914 | 0.86 | AXL (0.76) | AXLAURKAAURKBNEK2PTK2 | |
| Dubermatinib SCHEMBL30437663 | 0.86 | AXL (0.87) | AXLAURKAAURKBNEK2PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022261504-A1 | DENDRIMER CONJUGATES AND METHODS OF USE THEREOF | Ashvattha Therapeutics, Inc. (US) | 2022-12-15 | — | — | WO | disclosed |