SCHEMBL2472765

SCHEMBL2472765

CC=CC(=O)OCC(C)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
HCAR2 Q8TDS4 5/20 0.36
GSTP1 P09211 1/20 0.35
GABRR1 P24046 2/20 0.34
CYP1A2 P05177 1/20 0.34
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28082886 0.84 TSHR (0.30) TSHR
SCHEMBL28082890 0.83
SCHEMBL28082910 0.83
SCHEMBL28082981 0.83 GABRR1 (0.32) GABRR1
Crotonic Acid SCHEMBL28124165 0.83 TSHR (0.53) TSHRHCAR2ALDH1A1HPGD
SCHEMBL28245093 0.82 HCAR2 (0.38) TSHRHCAR2GSTP1ALDH1A1HPGD
SCHEMBL1532470 0.81 TSHR (0.59) TSHRHCAR2GSTP1ALDH1A1HPGD
SCHEMBL182262 0.81 TSHR (0.59) TSHRHCAR2GSTP1ALDH1A1HPGD
SCHEMBL182261 0.81 TSHR (0.59) TSHRHCAR2GSTP1ALDH1A1HPGD
SCHEMBL20657975 0.80 PGK1 (0.39) TSHRHCAR2GSTP1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070010690-A1 Process for manufacturing high purity methacrylic acid DECOURCY MICHAEL S 2007-01-11 US claimed
EP-1493728-A1 Process for manufacturing high purity methacrylic acid ROHM AND HAAS COMPANY (US) 2005-01-05 EP claimed
US-20040267050-A1 Process for manufacturing high purity methacrylic acid DECOURCY MICHAEL STANLEY (US) 2004-12-30 US claimed
WO-2024024868-A1 ANTIFOULING COATING COMPOSITION 中国塗料株式会社 2024-02-01 WO disclosed
EP-3480268-B1 ANTIFOULING COATING COMPOSITION, ANTIFOULING COATING FILM, BASE MATERIAL PROVIDED WITH ANTIFOULING COATING FILM, METHOD FOR PRODUCING SAME, AND ANTIFOULING METHOD CHUGOKU MARINE PAINTS (JP) 2023-09-13 EP disclosed
EP-3480267-B1 ANTIFOULING COATING MATERIAL COMPOSITION, ANTIFOULING COATING FILM, SUBSTRATE PROVIDED WITH ANTIFOULING COATING FILM AND PRODUCTION METHOD THEREFOR, AND ANTIFOULING METHOD CHUGOKU MARINE PAINTS (JP) 2023-09-06 EP disclosed
US-20230123769-A1 ANTIFOULING COATING COMPOSITION CHUGOKU MARINE PAINTS, LTD. (JP) 2023-04-20 US disclosed
EP-4119620-A1 ANTIFOULING COATING COMPOSITION Chugoku Marine Paints, Ltd. (JP) 2023-01-18 EP disclosed
US-11254823-B2 Antifouling coating material composition, antifouling coating film, substrate provided with antifouling coating film and production method therefor, and antifouling method CHUGOKU MARINE PAINTS, LTD. (JP) 2022-02-22 US disclosed
US-20200056055-A1 ANTIFOULING COATING COMPOSITION, ANTIFOULING COATING FILM, SUBSTRATE WITH ANTIFOULING COATING FILM AND METHOD FOR PRODUCING SAME, AND ANTIFOULING METHOD CHUGOKU MARINE PAINTS, LTD. (JP) 2020-02-20 US disclosed
US-20190330479-A1 ANTIFOULING COATING MATERIAL COMPOSITION, ANTIFOULING COATING FILM, SUBSTRATE PROVIDED WITH ANTIFOULING COATING FILM AND PRODUCTION METHOD THEREFOR, AND ANTIFOULING METHOD CHUGOKU MARINE PAINTS, LTD. (JP) 2019-10-31 US disclosed
EP-2377843-B1 Method for purifying methacrylic acid-containing streams ROHM & HAAS (US) 2014-01-15 EP disclosed
EP-2377843-A1 Method for purifying methacrylic acid-containing streams Rohm and Haas Company (US) 2011-10-19 EP disclosed
EP-2371803-A1 Method for purifying a HIBA-containing methacrylic acid stream Rohm and Haas Company (US) 2011-10-05 EP disclosed
US-7723541-B2 Process for manufacturing high purity methacrylic acid ROHM AND HAAS COMPANY (US) 2010-05-25 US disclosed
US-20070010690-A1 Process for manufacturing high purity methacrylic acid DECOURCY MICHAEL S 2007-01-11 US disclosed
JP-2005023060-A MANUFACTURING METHOD OF HIGH PURITY METHACRYLIC ACID ROHM & HAAS CO 2005-01-27 JP disclosed
EP-1493729-A1 Process for manufacturing high purity methacrylic acid Rohm and Haas Company (US) 2005-01-05 EP disclosed
EP-1493728-A1 Process for manufacturing high purity methacrylic acid ROHM AND HAAS COMPANY (US) 2005-01-05 EP disclosed
US-20040267050-A1 Process for manufacturing high purity methacrylic acid DECOURCY MICHAEL STANLEY (US) 2004-12-30 US disclosed