Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.60 |
| ▸ | EGFR | P00533 | 5/20 | 0.58 |
| ▸ | ITK | Q08881 | 3/20 | 0.58 |
| ▸ | AURKA | O14965 | 10/20 | 0.52 |
| ▸ | BTK | Q06187 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 3/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.49 |
| ▸ | ULK1 | O75385 | 2/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.49 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.49 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.49 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.49 |
| ▸ | CDC7 | O00311 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | PLK4 | O00444 | 1/20 | 0.49 |
| ▸ | STK25 | O00506 | 1/20 | 0.49 |
| ▸ | CIT | O14578 | 1/20 | 0.49 |
| ▸ | RIOK3 | O14730 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24728144 | 0.81 | SYK (0.56) | SYKEGFRITKAURKABTK | |
| SCHEMBL656977 | 0.81 | SYK (0.69) | SYKEGFRITKAURKABTK | |
| SCHEMBL24728125 | 0.78 | SYK (0.60) | SYKEGFRITKAURKABTK | |
| SCHEMBL30086260 | 0.76 | PTK2 (0.72) | SYKEGFRITKAURKAKDR | |
| SCHEMBL23754871 | 0.76 | PTK2 (0.72) | SYKEGFRITKAURKAKDR | |
| SCHEMBL1035775 | 0.76 | EGFR (0.81) | SYKEGFRITKAURKABTK | |
| SCHEMBL656345 | 0.74 | SYK (0.74) | SYKEGFRITKAURKA | |
| SCHEMBL28294288 | 0.73 | SYK (0.67) | SYKEGFRITKAURKABTK | |
| SCHEMBL12726126 | 0.73 | SYK (0.70) | SYKEGFRITKAURKABTK | |
| SCHEMBL12518713 | 0.73 | EGFR (1.00) | SYKEGFRITKBTKJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220388968-A1 | INHIBITORS OF ERYTHROCYTE BAND 3 TYROSINE PHOSPHORYLATION AND USES THEREOF | PURDUE RESEARCH FOUNDATION | 2022-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220388968-A1 | INHIBITORS OF ERYTHROCYTE BAND 3 TYROSINE PHOSPHORYLATION AND USES THEREOF | SPTBN1, CTTN, HBG1 | SYK 94/4885EGFR 3701/4885ITK 952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.