Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.76 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HMGCR | P04035 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SNCA | P37840 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | JUN | P05412 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29931173 | 1.00 | NFE2L2 (0.76) | NFE2L2ABCG2KDM4EHMGCRCYP3A4 | |
| SCHEMBL2744488 | 0.86 | NFE2L2 (1.00) | NFE2L2ABCG2KDM4EHMGCRCYP3A4 | |
| SCHEMBL2744657 | 0.86 | NFE2L2 (1.00) | NFE2L2ABCG2KDM4EHMGCRCYP3A4 | |
| SCHEMBL715804 | 0.85 | NFE2L2 (0.76) | NFE2L2ABCG2KDM4EHMGCRCYP3A4 | |
| SCHEMBL30871940 | 0.85 | NFE2L2 (0.76) | NFE2L2ABCG2KDM4EHMGCRCYP3A4 | |
| SCHEMBL715805 | 0.85 | NFE2L2 (0.76) | NFE2L2ABCG2KDM4EHMGCRCYP3A4 | |
| SCHEMBL9907024 | 0.84 | NFE2L2 (0.65) | NFE2L2ABCG2KDM4EHMGCRCYP3A4 | |
| SCHEMBL3675045 | 0.83 | NFE2L2 (0.73) | NFE2L2ABCG2KDM4EHMGCRCYP3A4 | |
| SCHEMBL14875237 | 0.83 | NFE2L2 (0.73) | NFE2L2ABCG2KDM4EHMGCRCYP3A4 | |
| SCHEMBL14875236 | 0.83 | NFE2L2 (0.73) | NFE2L2ABCG2KDM4EHMGCRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022158624-A1 | NOVEL BENZOPYRAN DERIVATIVE COMPOUND, PREPARATION METHOD THEREFOR, AND ANTICANCER COMPOSITION COMPRISING SAME | 연세대학교 산학협력단 | 2022-07-28 | — | — | WO | disclosed |