Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 16/20 | 0.51 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | BRD2 | P25440 | 2/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.43 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17798114 | 0.90 | BRD4 (0.58) | BRD4C5AR1HPGDEP300CREBBP | |
| SCHEMBL17798099 | 0.86 | BRD4 (0.48) | BRD4C5AR1HPGDEP300CREBBP | |
| SCHEMBL17798076 | 0.85 | BRD4 (0.47) | BRD4C5AR1CREBBP | |
| SCHEMBL17798168 | 0.78 | BRD4 (0.58) | BRD4EP300CREBBPBRD2BRD3 | |
| SCHEMBL12098652 | 0.75 | BRD4 (0.51) | BRD4EP300CREBBPBRD2BRD3 | |
| SCHEMBL31499237 | 0.75 | BRD4 (0.50) | BRD4EP300CREBBP | |
| SCHEMBL31499256 | 0.75 | BRD4 (0.62) | BRD4 | |
| SCHEMBL29920839 | 0.74 | MIF (0.61) | BRD4 | |
| SCHEMBL17798015 | 0.74 | MIF (0.61) | BRD4 | |
| SCHEMBL17807864 | 0.74 | BRD4 (0.58) | BRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3674300-B1 | NOVEL BICYCLIC BROMODOMAIN INHIBITORS | ZENITH EPIGENETICS LTD (CA) | 2022-10-12 | — | — | EP | disclosed |