Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 12/20 | 0.50 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | PARG | Q86W56 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31499256 | 0.89 | BRD4 (0.62) | BRD4PARGLMNAPTGDR2 | |
| SCHEMBL31499235 | 0.85 | CREBBP (0.53) | BRD4CREBBP | |
| SCHEMBL31499245 | 0.83 | BRD4 (0.47) | BRD4EP300CREBBP | |
| SCHEMBL10146624 | 0.80 | GRM2 (0.60) | BRD4CREBBPPARG | |
| SCHEMBL17798168 | 0.77 | BRD4 (0.58) | BRD4EP300CREBBP | |
| SCHEMBL24728201 | 0.75 | BRD4 (0.51) | BRD4EP300CREBBP | |
| SCHEMBL17798166 | 0.75 | BRD4 (0.57) | BRD4EP300CREBBPLMNAPTGDR2 | |
| SCHEMBL29920772 | 0.75 | BRD4 (0.57) | BRD4EP300CREBBPLMNAPTGDR2 | |
| SCHEMBL16347918 | 0.75 | GRIN1 (0.67) | — | |
| SCHEMBL17798114 | 0.74 | BRD4 (0.58) | BRD4EP300CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504726-A | BRD4 inhibitor and preparation method and application thereof | 四川大学华西医院 | 2025-02-25 | — | — | CN | disclosed |