SCHEMBL24728275

SCHEMBL24728275

CNC(=O)N1CCCc2[nH]nc(C(=O)N3CCC(C)CC3)c2C1

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RBP4 P02753 19/20 0.57
PLA2G1B P04054 1/20 0.43
ATG4B Q9Y4P1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20589421 0.80 RBP4 (0.70) RBP4
SCHEMBL17232824 0.77 CREBBP (0.39) RBP4
SCHEMBL24727628 0.76 RBP4 (0.63) RBP4
SCHEMBL18798822 0.75 BAZ2B (0.40) RBP4PLA2G1BATG4B
SCHEMBL21334029 0.74 CREBBP (0.40) RBP4
SCHEMBL22958124 0.74 RBP4 (0.38) RBP4PLA2G1BATG4B
SCHEMBL17222881 0.73 RBP4 (1.00) RBP4
SCHEMBL17222898 0.73 RBP4 (1.00) RBP4
SCHEMBL17222883 0.73 RBP4 (0.88) RBP4
SCHEMBL24727812 0.73 RBP4 (0.64) RBP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4036094-A1 SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE The Trustees of Columbia University in the City of New York (US) 2022-08-03 EP disclosed