SCHEMBL24728748

SCHEMBL24728748

c1ccc2cc(-c3ccc(-c4ccc5ccc6c(-c7ccc(-c8ccc9ccccc9c8)cc7)ccc7ccc4c5c76)cc3)ccc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.52
ESR2 Q92731 4/20 0.52
GSTP1 P09211 1/20 0.47
ALOX5 P09917 1/20 0.46
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
HSD17B1 P14061 3/20 0.44
HSD17B2 P37059 3/20 0.44
CYP17A1 P05093 1/20 0.42
CYP19A1 P11511 1/20 0.42
CYP11B1 P15538 1/20 0.42
CYP11B2 P19099 1/20 0.42
CYP1A2 P05177 3/20 0.41
ERBB2 P04626 1/20 0.41
FYN P06241 1/20 0.41
MAOA P21397 1/20 0.41
ACHE P22303 1/20 0.41
AHR P35869 1/20 0.41
ALDH1A1 P00352 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3687907 0.92 GSTP1 (0.55) ESR1ESR2GSTP1ALOX5CA1
SCHEMBL3792915 0.92 GSTP1 (0.55) ESR1ESR2GSTP1ALOX5CA1
SCHEMBL25842113 0.92 CA12 (0.49) ESR1ESR2GSTP1ALOX5CA1
SCHEMBL31488899 0.90 ESR1 (0.43) ESR1ESR2GSTP1ALOX5CA1
SCHEMBL4153121 0.89 GSTP1 (0.48) ESR1ESR2GSTP1ALOX5CA1
SCHEMBL2789566 0.89 GSTP1 (0.52) ESR1ESR2GSTP1ALOX5HSD17B1
SCHEMBL2967928 0.87 CYP1A2 (0.46) ESR1ESR2GSTP1ALOX5CA1
SCHEMBL14101473 0.86 GSTP1 (0.40) ESR1ESR2GSTP1ALOX5CA1
SCHEMBL17120289 0.86 MEN1 (0.43) ESR1ESR2GSTP1ALOX5CA1
SCHEMBL14101641 0.86 ESR1 (0.40) ESR1ESR2GSTP1ALOX5CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3892705-B1 IRIDIUM COMPLEX-CONTAINING COMPOSITION, ORGANIC LIGHT EMITTING DEVICE HAVING THE SAME, DISPLAY APPARATUS, IMAGING APPARATUS, ELECTRONIC EQUIPMENT, LIGHTING APPARATUS, AND MOVING BODY CANON KK (JP) 2022-12-14 EP disclosed