SCHEMBL24728798

SCHEMBL24728798

CCCCC/C=C\CCOC(=O)CCCCCCCCCN(CCO)CCCCCCCCCC(=O)OCCCCCCCCCCN(CCO)CC/C=C\CCCCC

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.54
FAAH O00519 1/20 0.50
EPHX2 P34913 1/20 0.50
DGKA P23743 2/20 0.49
PRKCE Q02156 1/20 0.47
PRKCQ Q04759 1/20 0.47
PRKCD Q05655 1/20 0.47
PRKCA P17252 1/20 0.47
CNR2 P34972 2/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
THRB P10828 1/20 0.47
CNR1 P21554 1/20 0.47
DNM1 Q05193 1/20 0.47
TRPV1 Q8NER1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24728761 0.95 MGLL (0.59) MGLLFAAHEPHX2DGKAPRKCE
SCHEMBL20138973 0.95 MGLL (0.59) MGLLFAAHEPHX2DGKAPRKCE
SCHEMBL24728757 0.94 MGLL (0.53) MGLLFAAHEPHX2DGKAPRKCE
SCHEMBL24728782 0.92 MGLL (0.66) MGLLFAAHEPHX2DGKACNR2
SCHEMBL18641682 0.92 MGLL (0.66) MGLLFAAHEPHX2DGKACNR2
SCHEMBL32685078 0.92 MGLL (0.66) MGLLFAAHEPHX2DGKACNR2
SCHEMBL24728619 0.92 MGLL (0.66) MGLLFAAHEPHX2DGKACNR2
SCHEMBL24728610 0.92 MGLL (0.66) MGLLFAAHEPHX2DGKACNR2
SCHEMBL20618425 0.92 MGLL (0.66) MGLLFAAHEPHX2DGKACNR2
SCHEMBL24485282 0.92 MGLL (0.66) MGLLFAAHEPHX2DGKACNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022168085-A1 LIPIDS SUITABLE FOR NUCLEIC ACID DELIVERY RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2022-08-11 WO disclosed